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GABA Benefits, Uses, Side Effects and Functions

Discover the Function, Sources and Benefits of the Health Supplement Ingredient Gamma-Aminobutyric Acid, or GABA

Gamma-aminobutyric acid, more commonly known as GABA, is a non-protein amino acid that functions as a neurotransmitter. GABA and its precursor, glutamate, are the most abundant neurotransmitters in the central nervous system, particularly in the cerebral cortex. Glutamate is an excitatory neurotransmitter while GABA is an inhibitory neurotransmitter, so their actions are complementary. In addition to being produced within the body, GABA is also available as an ingredient in select health and bodybuilding supplements such as HGF MAX and HGH 30,000 Nanograms spray.

Functions of GABA

As an inhibitory neurotransmitter, GABA balances the excitatory effect of glutamate in the developed brain and helps to control cortical stimulation. Due to this action, GABA can have a calming or tranquilizing effect, including anxiolytic and anti-convulsive properties. Evidence suggests it may also stimulate human growth hormone (HGH) production, thereby serving as a natural HGH releaser.

Sources of GABA

GABA is produced by the body, where it is synthesized from glutamate through decarboxylation. While GABA is not naturally found in fresh foods, it can be created through lactobacillus fermentation; therefore, GABA may be consumed in fermented foods such as kimchi, sauerkraut, tempeh, miso, kefir and yogurt, as well as in GABA-fortified foods. In addition, foods that contain GABA’s precursors—glutamic acid or L-glutamine—can help boost GABA levels. Dietary sources of glutamate/glutamine include whole grains, brown rice, beef liver, pork, halibut, mackerel, lentils, broccoli, bananas and tree nuts. Vitamins B-6 and B-12 are required for GABA synthesis, so taking these vitamins may help support GABA production. Finally, GABA may also be consumed orally as an ingredient in natural dietary supplements.

GABA Benefits and Uses

Evidence has shown that GABA may help treat hypertension, so it is sometimes used in medications that are designed to lower blood pressure. The method of action appears to be due to GABA’s ability to suppress the sympathetic nervous activity that leads to high blood pressure. GABA’s anticonvulsant properties suggest that it may be effective in reducing the frequency of seizures in some individuals, while its calming effects may help reduce stress, relieve anxiety, elevate mood, and improve focus and concentration.

A number of studies have indicated that GABA may act as a natural HGH releaser, or HGH secretagogue. In light of its potential to stimulate HGH production, GABA-containing supplements are often taken to support lean muscle growth, decrease body fat and enhance exercise tolerance. Furthermore, GABA is believed to have an analgesic effect, so it may help to alleviate feelings of pain or soreness after an intense workout.

Side Effects of GABA and Potential Interactions

GABA supplementation is generally considered safe for healthy adults; no side effects have been reported at commonly administered dosages. However, since GABA has been shown to reduce blood pressure, supplements containing GABA may increase the risk of hypotension (abnormally low blood pressure) when taken in conjunction with antihypertensive drugs.

More detailed safety information on GABA side effects and interactions can be found in the Natural Medicines Comprehensive Database (subscription required). As with any medication or health supplement, it is best to consult your physician before taking dietary supplements containing GABA.

GABA Research and Studies

Many researchers have explored the use of GABA to treat medical conditions such as hypertension and anxiety. Numerous animal and human studies—including some published in the British Journal of Nutrition, Journal of Physiological Anthropology, Clinical and Experimental Hypertension, Journal of Agricultural and Food Chemistry, and Transgenic Research—have revealed GABA’s ability to lower blood pressure in cases of hypertension. Other studies have demonstrated its relaxing, immunity-enhancing and anti-anxiety effects. According to an article in BioFactors, GABA not only induces relaxation but also reduces anxiety; and evidence suggests it may enhance immunity under stress conditions. An animal study published Neuroscience found that GABA decreases anxiety-like behavior in rats. Furthermore, researchers documented GABA’s neuroprotective effects in the Journal of Microbiology and Biotechnology, which reported that GABA-producing Lactobacillus buchneri protected neuronal cells against neurotoxicant-induced cell death. Some researchers have explored the potential of GABA to be used in an analgesic capacity for pain relief—as described in Advances in Pharmacology, Neurochemical Research and the European Journal of Pharmacology—though further evidence is needed to accurately evaluate its effectiveness for this use.

Multiple studies have indicated that GABA is capable of promoting human growth hormone (HGH) secretion; relevant findings have been published in The Journal of Clinical Endocrinology and Metabolism, Acta Endocrinologica, Medicine and Sport Science, and other journals and textbooks. One study featured in Medicine and Science in Sports and Exercise examined the effect of GABA ingestion on immunoreactive growth hormone (irGH) and immunofunctional growth hormone (ifGH) release at rest and after exercise, and found that GABA elevates both resting and post-exercise HGH concentrations. Bodybuilders and athletes often take GABA supplements to help increase muscle growth, enhance muscle tone, burn fat and improve exercise tolerance. However, while GABA has been shown to stimulate HGH secretion, further clinical studies are needed to prove a direct correlation between GABA and other purported health and fitness benefits.

For additional GABA research, refer to the PubMed site sponsored by the National Institutes of Health (NIH).

HGH.com Supplements With GABA

Athletes, bodybuilders and fitness enthusiasts can leverage the potential benefits of GABA through natural health and bodybuilding supplements from HGH.com:

HGF MAX – Purity Select HGF MAX is intended to boost HGH production with a proprietary blend of ingredients, including GABA and key amino acids. This powerful dietary supplement can help improve muscle tone, build muscle, promote fat loss, boost energy and increase metabolism.

HGH Spray – HGH 30,000 Nanograms is designed to stimulate HGH release through a combination of GABA, L-group amino acids and other natural ingredients. Available in a convenient spray form, this product is formulated to support muscle growth, mass gain, fat burning and other benefits.

References (Function, Sources, Benefits/Uses and Side Effects/Interactions):

Clark, Josh. “Can Food Make People Happy?”; How Stuff Works; accessed May 13, 2015. <http://science.howstuffworks.com/life/food-happiness1.htm>

Examine.com. “GABA”; published under “Supplements”; accessed May 13, 2015. <http://examine.com/supplements/GABA>

Haas, Ryan. “The Effectiveness of GABA as a Weightlifting Supplement”; published in the “Sports and Fitness” section on Livestrong.com; October 24, 2013. <http://www.livestrong.com/article/442474-the-effectiveness-of-gaba-weight-lifting-supplement>

Hunt Renee. “A List of Foods With the Highest GABA”; published in the “Food and Health” section on Livestrong.com; April 19, 2015. <http://www.livestrong.com/article/478780-a-list-of-foods-with-the-highest-gaba>

Natural Medicines Comprehensive Database. “GABA (Gamma-Aminobutyric Acid)”; Natural Medicines Comprehensive Database; updated April 9, 2014. <http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=464&fs=ND&searchid=51623304>

Petroff, Ognen A.C. “GABA and Glutamate in the Human Brain”; Neuroscientist; December 2002. <http://www.ncbi.nlm.nih.gov/pubmed/12467378>

Stellpflug, Craig. “For a Healthy Brain and Nervous System – Gotta Have GABA”; Natural News; August 13, 2012. <http://www.naturalnews.com/036778_GABA_brain_health_nervous_system.html>

WebMD and Natural Medicines Comprehensive Database. “GABA (Gamma-Aminobutyric Acid)”; published under “Vitamins & Supplements”; accessed May 13, 2015. <http://www.webmd.com/vitamins-supplements/ingredientmono-464-gaba%20%28gamma-aminobutyric%20acid%29.aspx?activeingredientid=464&activeingredientname=gaba%20%28gamma-aminobutyric%20acid%29>

Research Sources:

Abdou, Adham M.; S. Higashiguchi; et al. “Relaxation and Immunity Enhancement Effects of Aamma-Aminobutyric Acid (GABA) Administration in Humans”; BioFactors; 2006. <http://www.ncbi.nlm.nih.gov/pubmed/16971751>

Cavagnini, Francesco; Giampiero Benetti; et al. “Effect of Gamma-Aminobutyric Acid on Growth Hormone and Prolactin Secretion in Man: Influence of Pimozide and Domperidone”; The Journal of Clinical Endocrinology and Metabolism; October 1980. <http://www.ncbi.nlm.nih.gov/pubmed/7419665>

Cavagnini, Francesco; Cecilia Invitti; et al. “Effect of Acute and Repeated Administration of Gamma Aminobutyric Acid (GABA) on Growth Hormone and Prolactin Secretion in Man”; Acta Endocrinologica; February 1980. <http://www.ncbi.nlm.nih.gov/pubmed/7376786>

Cho, Yu Ran; Ji Yoon Chang; and Hae Choon Chang. “Production of β-Aminobutyric Acid (GABA) by Lactobacillus Buchneri Isolated from Kimchi and Its Neuroprotective Effect on Neuronal Cells”; Journal of Microbiology and Biotechnology; January 2007. <http://www.ncbi.nlm.nih.gov/pubmed/18051360>

Enna, S.J. and Kenneth E. McCarson. “The Role of GABA in the Mediation and Perception of Pain”; Advances in Pharmacology; 2006. <http://www.ncbi.nlm.nih.gov/pubmed/17175808>

Hayakawaa, Kazuhito; Masayuki Kimura; et al. “Effect of a Gamma-Aminobutyric Acid-Enriched Dairy Product on the Blood Pressure of Spontaneously Hypertensive and Normotensive Wistar-Kyoto Rats”; British Journal of Nutrition; September 2004. <http://www.ncbi.nlm.nih.gov/pubmed/15469644>

Kowaka, Emi; Yasuka Shimajiri; et al. “Field Trial of GABA-Fortified Rice Plants and Oral Administration of Milled Rice in Spontaneously Hypertensive Rats”; Transgenic Research; December 2014. <http://www.ncbi.nlm.nih.gov/pubmed/25542346>

McCarson, Kenneth E. and S.J. Enna. “GABA Pharmacology: The Search for Analgesics”; Neurochemical Research; October 2014. <http://www.ncbi.nlm.nih.gov/pubmed/24532294>

Munro, Gordon; Rikke R. Hansen; and Naheed R. Mirza. “GABA(A) Receptor Modulation: Potential to Deliver Novel Pain Medicines?”; European Journal of Pharmacology; September 15, 2013. <http://www.ncbi.nlm.nih.gov/pubmed/23500203>

Okita, Yoshimitsu; Harunobu Nakamura; et al. “Effects of Vegetable Containing Gamma-Aminobutyric Acid on the Cardiac Autonomic Nervous System in Healthy Young People”; Journal of Physiological Anthropology; 2009. <http://www.ncbi.nlm.nih.gov/pubmed/19483370>

Powers, M. “GABA Supplementation and Growth Hormone Response”; Medicine and Sport Science; 2012. <http://www.ncbi.nlm.nih.gov/pubmed/23075553>

Powers, Michael E.; Joshua F. Yarrow; et al. “Growth Hormone Isoform Responses to GABA Ingestion at Rest and after Exercise”; Medicine and Science in Sports and Exercise; January 2008. <http://www.ncbi.nlm.nih.gov/pubmed/18091016>

Shimada, Morio; Takashi Hasegawa; et al. “Anti-Hypertensive Effect of Gamma-Aminobutyric Acid (GABA)-Rich Chlorella on High-Normal Blood Pressure and Borderline Hypertension in Placebo-Controlled Double Blind Study”; Clinical and Experimental Hypertension; June 2009. <http://www.ncbi.nlm.nih.gov/pubmed/19811362>

Vaz, Gisele Cristiane; Ana Paula Oliveira Bahia; et al. “Cardiovascular and Behavioral Effects Produced by Administration of Liposome-Entrapped GABA Into the Rat Central Nervous System”; Neuroscience; January 29, 2015. <http://www.ncbi.nlm.nih.gov/pubmed/25446344>

Yoshimura, Mineka; Tohru Toyoshi; et al. “Antihypertensive Effect of a γ-Aminobutyric Acid Rich Tomato Cultivar ‘DG03-9’ in Spontaneously Hypertensive Rats”; Journal of Agricultural and Food Chemistry; January 13, 2010. <http://www.ncbi.nlm.nih.gov/pubmed/20050705>




Exercise Videos and Tips for Arthritis & Aging

Exercise Videos and Tips for Arthritis & Aging

Whether you're trying to control pain or weight, need to lower your blood pressure or just want to feel better, exercise is known to provide these and numerous other health benefits. If you have arthritis or other aches and pains associated with aging, exercise can be instrumental in decreasing joint paint, reducing joint stiffness, improving flexibility, increasing mobility and enhancing overall wellness.

When you have arthritis or other aches and pains that tend to happen as you age, the thought of exercising can be very intimidating. However, the rewards and benefits by doing certain exercises can pay off with huge benefits to your body and quality of life. To give you the encouragement you may need, we have gathered together some great exercise videos and tips to get you started. We've also created a Pinterest board with plenty more tips for exercising as you age or if you have arthritis.

Exercises for People with Hip and Knee Arthritis

A professional physical therapist gives us some non-weight-bearing exercises that can be beneficial for someone who has arthritis in the hip or knee areas. The first exercise is a straight-leg raise, which uses the quadricep muscles and hip flexors. Increasing the intensity is as easy as adding an ankle weight to this exercise. The second exercise we learn about is a bridge, where the gluteus maximus is lifted and works the quadriceps and hamstrings, as well as hip and back extensors. The last exercise demonstrated is a side leg raise, which strengthens the hip abductor. These three exercises target the hip and knee areas, while focusing on strengthening the muscles around the joint, reducing the shock absorption and taking stress off of the joints. Check out this Exercise for Arthritis & Aging: Hip & Knee Arthritis Exercises video for the full presentation of each exercise.

Top 10 Exercises for Osteoarthritis of the Knee&lt

Have osteoarthritis of the knee? The team at the Good Exercise Guide, a group of medical professionals who focus on providing treatment and advice for individuals who need exercise as part of their recovery, created this video. It contains 10 of the best exercises to help individuals with osteoarthritis of the knee. There isn’t any audio, but the visual really says it all as the demonstrator does each exercise. You can follow along in real time for each of these exercises:

  • Long Sitting Calf Stretch
  • Towel Assisted Knee Mobility
  • Short-Arc Quadriceps Exercise
  • Bridging Exercise: Stage 1
  • Prone Knee Bends
  • Sitting Hamstring Stretch
  • Medial Quadriceps Mini Lunge
  • Best Inner-Range Quads Exercise
  • Safe Squats
  • 1Double Heel Raise

Tips for Protecting Your Joints

As you do everyday things like bending or picking up a box, you want to ensure that you are protecting your joints, especially when you have arthritis. This video shows how you can avoid lingering pain by protecting your joints during upper and lower body exercises when you have arthritis. The professional physical therapist and his client demonstrate positioning your body properly, along with the body mechanics of joints, muscles and ligaments to squat or bend to pick up something off of the floor.

Exercises for Arthritis and Aging Pinterest Board

Explore more tips and videos posted at our HGH.com Pinterest board dedicated to Exercises for Arthritis and Aging.

Follow Bodybuilding's Exercises for Arthritis and Aging Pinterest board.




L-Ornithine Benefits, Uses, Side Effects and Functions

Discover the Function, Sources and Benefits of the Health Supplement Ingredient L-Ornithine, or (S)-2,5-Diaminopentanoic Acid

Ornithine – also known as L-ornithine, (S)-2,5-diaminopentanoic acid or (S)-alpha,delta-diaminovaleric acid – is a crystalline amino acid. Different sources refer to it as a nonessential or conditionally essential amino acid, which means that it is normally produced by the body in sufficient amounts; however, dietary supplementation may be beneficial in times of illness, injury or stress. L-ornithine is found in some food sources as well as in health and bodybuilding supplements such as HGH 30,000 Nanograms pills and HGF MAX.

Functions of L-Ornithine

Together with arginine and citrulline, ornithine is one of three amino acids that play a key role in the urea cycle. The conversion of arginine into ornithine and ornithine into citrulline increases urea production while lowering ammonia concentrations in the blood. Citrulline subsequently binds with aspartate to form arginosuccinate, which breaks down into free arginine and fumarate; through this process, ornithine is metabolized back into arginine by the liver. Because L-ornithine helps accelerate the excretion of ammonia, it is believed to promote proper liver function, prevent fatigue and enhance performance during prolonged exercise. Evidence also suggests that L-ornithine may stimulate human growth hormone (HGH) production, thereby serving as a natural HGH releaser.

Sources of L-Ornithine

The human body manufactures ornithine from the amino acid arginine as part of the urea cycle. Dietary sources of L-ornithine include protein-rich foods such as beef, chicken, pork, fish, eggs, dairy products, peanuts and soybeans. L-ornithine may also be consumed in natural dietary supplements.

L-Ornithine Benefits and Uses

Among the benefits of ornithine is its ability to detoxify ammonia levels in the bloodstream; because of this function, it can be used to treat hepatic encephalopathy (a brain complication caused by liver disease). It also appears to help reduce fatigue and mitigate the effects of alcohol consumption, improving sleep quality and decreasing negative feelings the next morning. In addition, L-ornithine may promote wound healing, contribute to immune system function, support weight management, reduce stress and improve overall mood. Some evidence suggests L-ornithine acts as a natural HGH releaser, or HGH secretagogue. Because of its ability to boost HGH production and reduce fatigue, L-ornithine supplements are often taken to improve athletic performance, enhance muscle growth and increase endurance.

Side Effects of L-Ornithine and Potential Interactions

L-ornithine supplements are generally considered safe for adults; no serious side effects or drug interactions have been reported at doses of 2 to 6 grams per day. However, excessive doses (more than 10 grams per day) may potentially cause intestinal distress or diarrhea in some users.

More detailed safety information on L-ornithine dosing, side effects and interactions can be found on Examine.com. As with any medication or health supplement, it is best to consult your physician before taking dietary supplements containing L-ornithine.

L-Ornithine Research and Studies

Various research studies have shown that L-ornithine can be used therapeutically for certain medical conditions as well as to enhance overall health, well being and athletic performance. For example, a group of Polish researchers reported that L-ornithine-L-aspartate (LOLA) supplementation has the ability to lower blood ammonia concentration, eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis and stimulate tissue regeneration, while a Japanese study determined that healthy office workers who consumed a combination of caffeine and ornithine had higher mood ratings, less fatigue and better concentration than those who consumed caffeine alone. Japanese researchers also tested the effects of L-ornithine on salivary cortisol, mood and feelings of fatigue the morning after alcohol consumption, and found that L-ornithine supplements lowered cortisol levels, increased sleep length and significantly decreased feelings of fatigue, anger/hostility and confusion.

Study findings published in the Nutrition Journal and Nutrition Research revealed that L-ornithine not only has the potential to relieve stress and improve sleep quality in fatigued office workers, but also to reduce physical fatigue during exercise. Researchers stated that the decrease in physical fatigue is due to L-ornithine’s ability to modulate lipid and amino acid metabolism, thereby increasing the efficiency of energy consumption. Furthermore, a recent animal study published in the Brain Research Bulletin found that L-ornithine reduced body weight, abdominal fat and food intake in rats.

Beyond the research indicating L-ornithine’s potential to reduce fatigue and overall body weight, several studies suggest that it can improve strength and HGH levels. A study published in the Journal of Sports Medicine and Physical Fitness revealed that arginine and ornithine supplementation paired with a high-intensity strength-training program increased total strength and lean body mass in a relatively short period of time. The article also reported that the arginine and ornithine supplements aided in recovery from chronic stress by quelling tissue breakdown, as evidenced by lower urinary hydroxyproline levels. Furthermore, a double-blind study published in the Journal of Strength and Conditioning Research found that ornithine and arginine supplementation increased human growth hormone (HGH) and insulin-like growth factor-1 (IGF-1) serum levels after heavy-resistance exercise in strength-trained athletes. While further research is needed, the preliminary findings on L-ornithine supplements show significant promise for improving athletic performance, building muscle and elevating HGH levels.

For additional L-ornithine research, refer to the PubMed site sponsored by the National Institutes of Health (NIH).

HGH.com Supplements With L-Ornithine

Athletes, bodybuilders and fitness enthusiasts seeking to leverage the benefits of L-ornithine can find this amino acid among the ingredients in natural health and bodybuilding supplements from HGH.com:

HGH Pills – Purity Select’s HGH 30,000 Nanograms pills are formulated to boost growth hormone production with a powerful combination of L-group amino acids, including L-ornithine. As one of HGH.com’s best-selling products, these capsules help promote muscle growth, increased energy, fat-burning and other health benefits.

HGF MAX – Scientifically designed to increase HGH production, these Purity Select capsules contain a proprietary blend of ingredients including L-ornithine and other key amino acids. Taking HGF MAX as a dietary supplement can help build muscle, enhance muscle tone, improve stamina and increase metabolism.

References (Function, Sources, Benefits/Uses and Side Effects/Interactions):

Busch, Sandi. “Benefits of L-Arginine and L-Ornithine”; published in the “Nutrition Facts” section on Livestrong.com; July 13, 2014. <http://www.livestrong.com/article/502331-the-benefits-of-l-arginine-ornithine>

Examine.com. “Ornithine”; published under “Supplements”; accessed April 13, 2015. <http://examine.com/supplements/Ornithine>

Marie, Joanne. “What Does the Amino Acid L-Ornithine Do?”; published in the “Alternative Remedies” section on Livestrong.com; May 14, 2014. <http://www.livestrong.com/article/22017-amino-acid-l-ornithine>

National Center for Biotechnology Information, U.S. National Library of Medicine. “L-ornithine”; Compound Summary for CID 6262 in PubChem Open Chemistry Database; accessed April 13, 2015. <http://pubchem.ncbi.nlm.nih.gov/compound/L-ornithine>

Somera, Anna Lisa. “Foods With Ornithine”; published in the “Vitamins and Supplements” section on Livestrong.com; August 16, 2013. <http://www.livestrong.com/article/165604-foods-with-ornithine>

University of Maryland Shore Regional Health. “Amino Acids”; published in the “Medical Reference Guide” section; last updated April 23, 2014. <http://umm.edu/system-hospital-sites/shore-health/health/medical/ency/articles/amino-acids>

WebMD and Natural Medicines Comprehensive Database. “Ornithine”; published under “Vitamins & Supplements”; accessed April 13, 2015. <http://www.webmd.com/vitamins-supplements/ingredientmono-200-ornithine.aspx?activeingredientid=200&activeingredientname=ornithine>

Research Sources:

Demura, Shinichi; Takayoshi Yamada; et al. “The Effect of L-Ornithine Hydrochloride Ingestion on Performance During Incremental Exhaustive Ergometer Bicycle Exercise and Ammonia Metabolism During and After Exercise”; European Journal of Clinical Nutrition; October 2010. <http://www.ncbi.nlm.nih.gov/pubmed/20717126>

Elam, R.P.; D.H. Hardin; et al. “Effects of Arginine and Ornithine on Strength, Lean Body Mass and Urinary Hydroxyproline in Adult Males”; Journal of Sports Medicine and Physical Fitness; March 1989. <http://www.ncbi.nlm.nih.gov/pubmed/2770269>

Kokubo, Takeshi; Emiko Ikeshima; et al. “A Randomized, Double-Masked, Placebo-Controlled Crossover Trial on the Effects of L-Ornithine on Salivary Cortisol and Feelings of Fatigue of Flushers the Morning After Alcohol Consumption”; Biopsychosocial Medicine; February 18, 2013. <http://www.ncbi.nlm.nih.gov/pubmed/23414576>

Konishia, Yuuki; Yasutaka Koosaka; et al. “L-Ornithine Intake Affects Sympathetic Nerve Outflows and Reduces Body Weight and Food Intake in Rats”; Brain Research Bulletin; February 2015. <http://www.ncbi.nlm.nih.gov/pubmed/25526897>

Misaizu, Akane; Takeshi Kokubo; et al. “The Combined Effect of Caffeine and Ornithine on the Mood of Healthy Office Workers”; Preventative Nutrition and Food Science; December 2014. <http://www.ncbi.nlm.nih.gov/pubmed/25580405>

Miyake, Mika; Takayoshi Kirisako; et al. “Randomised Controlled Trial of the Effects of L-Ornithine on Stress Markers and Sleep Quality in Healthy Workers”; Nutrition Journal; June 3, 2014. <http://www.ncbi.nlm.nih.gov/pubmed/24889392>

Sikorska, Hanna; Janusz Cianciara; and Alicja Wiercińska-Drapało. “Physiological Functions of L-Ornithine and L-Aspartate in the Body and the Efficacy of Administration of L-Ornithine-L-Aspartate in Conditions of Relative Deficiency” (article published in Polish); Polski Merkuriusz Lekarski; June 2010. <http://www.ncbi.nlm.nih.gov/pubmed/20642112>

Sugino, Tomohiro; Tomoko Shirai; et al. “L-Ornithine Supplementation Attenuates Physical Fatigue in Healthy Volunteers by Modulating Lipid and Amino Acid Metabolism”; Nutrition Research; November 2008. <http://www.ncbi.nlm.nih.gov/pubmed/19083482>

Zajac, Adam; Stanisław Poprzęcki; et al. “Arginine and Ornithine Supplementation Increases Growth Hormone and Insulin-Like Growth Factor-1 Serum Levels After Heavy-Resistance Exercise in Strength-Trained Athletes”; Journal of Strength and Conditioning Research; April 2010. <http://www.ncbi.nlm.nih.gov/pubmed/20300016>




Online Supplement Store HGH.com Celebrates Brand Milestones Over 12-Year History

Bodybuilding and Natural Human Growth Hormone Supplement Company HGH.com Celebrates Brand Milestones Over 12-Year History

HGH.com was recently featured in Yahoo Finance, The Street, Region 8 ABC News, Health Technology.net, Pharmacy Choice, and many more top media outlets

"HGH.com has grown and evolved significantly over the past 12 years; but one thing that hasn't changed is our long-standing history of excellence," asserted Dan Smith of HGH.com. "We have earned a reputation for the highest-quality, most effective HGH supplements on the market, and our customers include everyone from amateur and professional bodybuilders to fitness enthusiasts and health buffs. And while we're committed to delivering the industry's best products, we're equally focused on providing an exceptional customer experience."

Smith notes that HGH.com is much more than an online vitamin and supplement store; he has continually added information, tools and resources through the years to create an extensive knowledge base for anyone looking to learn more about human growth hormones or obtain advice on nutrition and fitness. Consumers and the public at large can visit the HGH.com blog for detailed information on natural HGH supplement ingredients and uses, and for fitness and bodybuilding tips from IFBB pros and other experts. Additional resources are available on the HGH.com Facebook page, Twitter profile and YouTube channel.

"I'd like to thank our loyal customers for their ongoing support of HGH.com; our 12 years in business are a testament to their belief in us and the effectiveness of our products," said Smith. "We pledge to continue offering the industry's best natural HGH supplements, and we intend to upgrade our formulations and expand our product lines based on nutraceutical research as well as input from our IFBB pros and customers. I encourage consumers and the public to reach out to us with their questions, feedback and suggestions—we welcome it all!"

HGH.com Highlights Brand Evolution and Expansion, From Anti-Aging Solutions to a Full Range of Natural Health and Bodybuilding Supplements Created With Input From IFBB Pros - Read the full story on Yahoo Finance - http://finance.yahoo.com/news/bodybuilding-natural-human-growth-hormone-124000821.html.




HGF MAX - Human Growth Hormone Releaser and Booster

 
HGF Max will 
increase your HGH levels

HGF-MAX

 
Between the ages of 30 to 40, a person’s pituitary gland begins to slow down production of your human growth hormone. Because of this change, the body starts to show signs of aging such as decreased muscle mass, increased fatty deposits, sagging skin, etc... Human growth hormone helps to keep us looking and feeling young, which is why taking HGH supplements can be a highly effective way of maintaining those desired aspects of youth. In particular, the HGH supplement HGF-MAX can slow and reverse the aging process when taken regularly.
 
 
What is HGF-MAX?
 
HGF-MAX is a human growth hormone supplement that functions exactly like the body’s own version of HGH. However, because the pituitary gland decreases production of the human growth hormone as we age, the body begins to break down. No longer can we as easily maintain our muscle mass. Instead we gain fatty deposits, especially around the midsection, which can result in serious health issues such as heart disease and type 2 diabetes. Also, our bone density begins to deteriorate. Our skin loses its elasticity. Though these are all symptoms of diminished human growth hormone levels, HGF-MAX can act as a useful substitute for our body’s lack of natural HGH, and you can help your body return back to its youth form!


How does HGF-MAX work?
 
HGF-MAX functions like many other anti-aging supplements. Once introduced to the body, it immediately begins to repair and reverse the signs of aging. Because the human growth hormone is responsible for maintaining numerous bodily features such as the skeletal, muscular and dermal systems, HGF-MAX can change a person’s entire body. Muscle mass will increase, fatty deposits will shrink and the skin will regain its former suppleness. In effect, this HGH supplement can return the body to a healthier and more vital state.
 
What are the benefits of using HGF-MAX?
 
Using an HGH supplement like HGF-MAX has dual benefits. First, it can give a person a more youthful appearance by preventing both wrinkles and fatty deposits from forming. Rather than enlisting the aid of more invasive procedures like plastic surgery, you can instead take the human growth hormone HGF-MAX to regain the aesthetic appeal of youth. Second, HGH supplements such as HGF-MAX can change the body from inside out. Not only does it increase bone density, which cuts down the chances of serious injury due to a fall or other accident, but also it works to stave off those fatty deposits that prove to be dangerous to one’s health. Heart disease and type 2 diabetes are both major medical issues facing many individuals today. However, human growth hormones can be used to prevent these conditions from arising later in life.
 
 
Getting older generally holds a negative connotation. Though we cannot turn back time, that doesn’t mean we have to accept the changes that typically come with age. The human growth hormone HGF-MAX can return the vitality and health of our youth and offers several benefits. Not only can HGF-MAX save a person’s physical image, but it can also save a person’s health and life. 


Buy HGF MAX - HGH Supplement

 




Benefits of HGH - Human Growth Hormone

How HGH can Slow Aging

 
 
The pituitary gland and its production of the human growth hormone are responsible for helping children physically mature during adolescence. However, HGH is just as important for adults. Among its numerous benefits, the human growth hormone helps maintain the strength of our muscular and skeletal systems. Yet once production begins to decline in our 30s and beyond, we then notice signs of aging like increased fatty deposits, weaken bones and decreased skin elasticity. However, HGH supplements can stall these unwanted effects of aging, and in many cases, even reverse them.
 
HGH Increases Muscle Mass
 
As one ages, the ability to sustain and increase muscle mass becomes a difficult task. The human growth hormone regulates muscular strength and density, so a lack of it results in a weakened bodily state. Using HGH supplementsas a part of one’s health regimen can give the body a much needed boost toward maintaining the muscular system and even increasing muscle mass.
 
HGH Reduces Body Fat
 
Upon turning 40, some people experience what is commonly called “middle-age spread.” Regardless of diet or exercise, it becomes harder and harder to keep the stomach area from storing up fatty deposits. What’s worse is that studies have found that collecting fat around one’s mid-section can result in more serious health issues such as heart disease or diabetes. Human growth hormone pills can counter this risk to one’s health. HGH supplements stave off the accumulation of fat around the stomach and vital organs, thus helping to avoid a potential heart attack or a worse health condition down the road. 
To Burn Fat - See Somatropinne HGHHGF MaxClen XDV.
 
 
HGH Strengthens Bone Density
 
Bones become more brittle and susceptible to breakage as one ages. Whereas a fall at 20 may cause a few bumps and bruises, the very same act could result in a broken hip at 60. However, anti-aging supplements can be used to ward off bone density deterioration. HGH pills work to maintain bone tissue, and together with a healthy diet and regular exercise, can actually increase skeletal strength.
Strengthen Bone Density - See Somatropinne HGHHGF MaxHGH 30,000 Spray, and Growth Factor Plus
 
 
HGH Improves Skin Appearance
 
Wrinkles may not be considered a life-threatening circumstance, but many people think of them as among the worst signs of aging. When the body decreases production of the human growth hormones, skin decreases in elasticity as well. It loses its tautness and begins to sag and look sallow. Yet HGH pills can reverse these highly unwanted effects of getting older. By restoring previous levels of the human growth hormone, the skin can quite literally bounce back from its former state. It will once again regain its suppleness and give off the appearance of health and vitality.
 
Improve Skin Appearance - See Somatropinne HGHHGF MaxHGH 30,000 Spray, and HGH 30,000 Pills

Getting older doesn’t need to be scorned. One can simply learn to age smarter with the use of HGH supplements. Human growth hormone pills can give back to a person his or her former strength and youthful appearance. No matter what signs of aging you have, HGH supplements can force back those undesirable effects of age and give anyone who uses them the ability to live a longer and more productive life.



The Ingredients in the top HGH Supplement "HGF MAX" - Helping you with Muscle Growth

We at HGH.com are excited to introduce another amazing HGH supplement called HGF MAX (HGF:Human Growth Factor).
 
Like ANA-GH, the benefits to this breakthrough HGH Pill are profound. There is truly nothing else like it on the market.
 
Here's a list and explanation of the ingredients and how it's going to help you raise your HGH Levels, build muscles, act as an anti-aging supplement, increase your strength and stamina, and more. HGF MAX is the most potent and best HGH Supplement on the market, period.
  1. L-Arginine: Triple Growth Hormone LevelsStudies show that Arginine can as much as triple your growth hormone levels, even in old age, and mixed with the ingredients within HGF MAX, it can as much as multiply them by TEN! It can also help improve your exercise performance for high-intensity, short duration work outs. It’s also been linked to helping Erectile Dysfunction due to its ability to increase blood flow. Further - It increases fat burning, builds muscle tissue, boosts immunity, promotes healing, enhances male fertility, and more!
  2. L-Glutamine
    L-Glutamine is essential to your body and is used by your body during times of stress. It's important to your body's muscle maintenance. It increases energy levels and is known to add mental focus and alertness. It's also helpful with cell growth. Other studies have shown it to boost your immunity, lower cholesterol levels and lower blood pressure.

  3. L-Lysine
    Lysine is an essential amino acid that the human body cannot produce naturally. Lysine works with the other essential amino acids in HGF MAX to maintain growth, lean body mass, and the body's store of nitrogen. Lysine with the other ingredients in HGF MAX can multiply your growth hormone levels by as much as 10 times! It can also help with your sexual stamina.
  4. L-Tyrosine
    Tyrosine is used by the thyroid gland for the production of Thyroxine, another vital hormone shown in clinical studies to help reduce fatigue and depression, as well as regulate growth and metabolism.
  5. Glycine
    Glycine is one of the key stimulatory agents that encourages your pituitary gland to secrete HGH! It also has a calming effect on the brain and may play a role in the health of the prostate. Studies show that a clear and significant increase of serum HGH was observed after people were given Glycine.
  6. Astragalus extract
    Astragalus is used to boost the body's immune system as well as treating health conditions such as heart disease. Its antioxidant effects inhibit free radical production, thus helping to repair damaged cells and help stave off some of the signs and symptoms associated with aging.
  7. Deer Antler Velvet 
    Deer Antler Velvet is a powerful and natural source of natural source of glucosamine, chondroitin and collagen that can help you boost your strength and performance. In the 1980s, scientists tested the effects of deer antler velvet on the performance of top athletes, and the results were astonishing. Deer antler velvet helped increase the strength and muscle mass of athletes, and speed their recovery time from exercise, enabling them to shatter records. Deer Antler Velvet is a must in Performance Enhancers.
  8. GABA (Gamma-Aminobutyric acid) 
    GABA (Gamma-aminobutyric acid) is essential for brain metabolism, and is made in the body from another amino acid, glutamic acid. As human growth hormone is produced in the brain by the pituitary, GABA HgH releaser influences the brain environment in a positive way to facilitate the production and release of growth hormone.
  9. Phosphatidyl Choline
    This acts as an excellent emulsifier, facilitating the absorption of the other nutrients included in our HGF MAX. Phosphatidyl Choline also breaks down fat deposits in the body, making it helpful in the prevention of gallstones, atherosclerosis, heart disease, and liver problems, depression, memory loss, and neurological disorders.
  10. L-Ornithine (L-Ornithine HCl)
    L-Ornithine is the most potent amino acid ever studied for stimulating the production and release ofHuman Growth Hormone from the pituitary gland. Studies of L-Ornithine have shown the ability to regenerate the thymus gland, liver, and heart tissue, enhance muscle growth, and increase immune system function.
In closing, you cannot miss out on HGF MAX. This is going to be another game changer by HGH.com and Purity Select!






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