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Whey Protein Benefits, Uses, Side Effects and Functions

Discover the Function, Sources and Benefits of the Health Supplement Ingredient Whey Protein

Whey protein and casein are the two major types of proteins in milk. While casein is digested more slowly, whey is a quickly and easily digested source of protein. It contains essential amino acids, including branched-chain amino acids (BCAAs), and its amino-acid profile is similar to that of human skeletal muscle. While whey protein is naturally found in dairy products, it is also available in a more concentrated form in dietary supplements. These include health and bodybuilding supplements such as CytoSport, IsoBolic, Multi-Pro and Elite whey protein powders.

Functions of Whey Protein

Protein contributes to the growth, development and repair of human tissue, so consuming whey protein can help to support these functions. The amino acids contained in whey protein play a critical role in regulating protein metabolism, and are believed to aid the body in transitioning from a catabolic state to an anabolic state following exercise. Furthermore, studies have suggested that whey protein may decrease fat stores in the body and increase feelings of satiety (fullness), thereby helping to regulate weight and body composition.

Sources of Whey Protein

Dairy products are a natural source of whey protein, which separates from milk during the cheese-making process. Among food sources, ricotta cheese contains the highest levels of whey protein; however, it can also be found in milk, yogurt and other cheeses. When whey protein is extracted and processed for use in natural dietary supplements, it can take one of several forms, including whey powder, whey protein concentrate and whey protein isolate. Of these, whey protein isolate contains the highest protein content, followed by whey protein concentrate and then whey powder.

Whey Protein Benefits and Uses

Consuming whey protein elevates the body’s overall levels of protein and essential amino acids, which help to maintain human skeletal muscles. As a result, whey protein is a popular ingredient in health and bodybuilding supplements, where it is used to increase muscle mass and strength as well as improve athletic performance. Because whey protein appears to decrease fat stores and create feelings of fullness, it is also used as an appetite suppressant and may be included as an ingredient in weight-loss supplements.

Another benefit of whey protein is its ability to lower blood-sugar levels, which may be helpful for individuals with milder cases of diabetes that can be controlled with proper diet and exercise. Whey protein is also used as an ingredient in baby formulas because it is an easily digested form of protein and provides important nutrients needed for growth and development. There are many other purported uses of whey protein – ranging from acid reflux to chronic lung conditions to psoriasis – though evidence in these areas is currently inconclusive.

Side Effects of Whey Protein and Potential Interactions

Whey protein is generally considered safe for most adults; users should follow the recommended dosage and directions listed on dietary supplements. Those who are lactose intolerant or have a known sensitivity to milk may find that some whey protein formulas can cause similar symptoms, such as bloating, cramps, diarrhea or nausea. When taken in high doses, whey protein may cause headaches, fatigue or thirst in some people.

Individuals taking certain types of medication should be aware of potential interactions. Whey protein may decrease the absorption of levodopa, alendronate and some antibiotics (including quinolone, fluoroquinolone and tetracycline). Since whey protein has been shown to lower blood-glucose levels, it can cause hypoglycemia when it is taken in combination with diabetes medications. When whey protein is taken in combination with blood thinners, it may increase the risk of bleeding.

More detailed safety information on whey protein side effects and interactions can be found on the Mayo Clinic website. As with any medication or health supplement, it is best to consult your physician before taking dietary supplements containing whey protein.

Whey Protein Research and Studies

Numerous studies have examined the effects of whey protein on muscle mass, muscle recovery, athletic performance and body composition. For example, recent animal studies published in the journals Nutrition and Medicine & Science in Sports & Exercise found that resistance exercise combined with whey protein led to significant muscle weight increases in rats and that whey protein supplementation improved exercise performance, body composition and biochemical assessments in mice.

Human trials also support the use of whey protein for post-exercise recovery and improved body composition. Research published in Amino Acids determined that whey protein may accelerate the muscle regeneration/remodeling process after high-intensity exercise, while the International Journal of Sport Nutrition and Exercise Metabolism reported that whey protein supplements taken by runners facilitated their recovery from strenuous training. In the Journal of the American College of Nutrition, researchers analyzed 14 randomized, controlled trials on generally healthy adults and found that whey protein supplements – either combined with resistance exercise or as part of a weight-loss or weight-maintenance diet – improved body composition parameters.

In addition, research findings suggest that whey protein supplements are beneficial for overweight and diabetic individuals. In the Journal of Applied Physiology, researchers studied overweight/obese adults who consumed whey protein supplements either with or without exercise and found that all of them lost body weight, fat mass and abdominal fat. Among those test subjects, the group that took whey protein supplements in combination with a multimode exercise training program lost significantly more body weight and gained a greater percentage of lean body mass. An article published in Diabetologia examined the impact of whey protein on diabetics, and determined that taking whey protein before breakfast helped to increase insulin levels and decrease glucose in patients with type 2 diabetes. For additional whey protein research reports, refer to the PubMed site sponsored by the National Institutes of Health (NIH).

HGH.com Supplements With Whey Protein

Athletes, bodybuilders and fitness enthusiasts rely on whey protein supplements to help build muscle, aid in post-exercise recovery and maintain a healthy weight. HGH.com offers a variety of natural health and bodybuilding supplements formulated with whey protein:

Elite Whey Protein Butter Toffee and Elite Whey Protein Chocolate Mint – Whey protein isolates, concentrate and peptides are combined with a proprietary digestive enzyme blend to enhance digestion and absorption of Elite Whey Protein supplements, which provide 23 grams of protein per serving. These delicious powdered-drink mixes help grow and strengthen muscle while aiding in muscle repair and recovery.

IsoBolic Cinnamon Oatmeal and IsoBolic Vanilla – The advanced protein matrix in IsoBolic supplements blends whey protein isolate and whey protein concentrate with other active ingredients, packing in 45 grams of protein per serving. These delicious powdered mixes support intense workouts, offering sustained protein release to stimulate muscle growth and recovery.

Multi-Pro Chocolate Whey Protein – Featuring whey protein isolate, whey protein concentrate and whey permeate, Multi-Pro Chocolate provides 24 grams of protein in each serving. This great-tasting, low-carb drink mix delivers vitamins and minerals in a complete protein supplement that helps users gain muscle while minimizing body fat.

CytoSport Vanilla Whey Protein – Made with whey protein concentrate and whey protein hydrolysate, each serving of CytoSport Vanilla Whey contains 18 grams of protein and provides essential nutrients and amino acids. This low-fat, low-lactose powder mixes easily and is biologically complete, helping users build lean muscle mass and recover more quickly after intense workouts.

Mega Shake Strawberry – Formulated with a powerful blend of active ingredients – including whey protein concentrates, isolates and peptides – Mega Shake offers 32 grams of total protein per serving. Its high-quality proteins, vitamins and minerals help increase muscle tone, reduce body fat, provide energy and support muscle recovery.


References (Function, Sources, Benefits/Uses and Side Effects/Interactions):

Mayo Clinic and The National Standard Research Collaboration. “Drugs and Supplements: Whey Protein”; National Standard Patient Monograph information published on Mayo Clinic website; last updated November 1, 2013. <http://www.mayoclinic.org/drugs-supplements/whey-protein/background/hrb-20060532>

Deuster, Patricia; Maier, Steven; et al. “Protein and Amino Acids Products – Whey Protein”; Dietary Supplements and Military Divers: A Synopsis for Undersea Medical Officers, published by Uniformed Services University of the Health Sciences; January 2004. <http://hprc-online.org/dietary-supplements/files/DietarySupplementUMO.pdf>

Bennett, Andrew. “Which Foods Contain Whey Protein?”; article published on Livestrong.com website; October 21, 2013. <http://www.livestrong.com/article/254097-which-foods-contain-whey-protein/>

Research Sources:

Arciero, Paul J.; Baur, Daniel; et al. “Timed-Daily Ingestion of Whey Protein and Exercise Training Reduces Visceral Adipose Tissue Mass and Improves Insulin Resistance: The PRISE Study”; Journal of Applied Physiology; July 1, 2014. <http://www.ncbi.nlm.nih.gov/pubmed/24833780>

Chen, Wen-Chyuan; Huang, Wen-Ching; et al. “Whey Protein Improves Exercise Performance and Biochemical Profiles in Trained Mice”; Medicine & Science in Sports & Exercise; August 2014. <http://www.ncbi.nlm.nih.gov/pubmed/24504433>

Farup, Jean; Rahbek, Stine Klejis; et al. “Whey Protein Supplementation Accelerates Satellite Cell Proliferation During Recovery From Eccentric Exercise”; Amino Acids; July 2014. <http://www.ncbi.nlm.nih.gov/pubmed/25063205>

Hansen, Mette; Bangsbo, Jens; et al. “Effect of Whey Protein Hydrolysate on Performance and Recovery of Top-Class Orienteering Runners”; International Journal of Sport Nutrition and Exercise Metabolism; published online ahead of print July 14, 2014. <http://www.ncbi.nlm.nih.gov/pubmed/25029703>

Haraguchi, Fabiano Kenji; de Brito Magalhães, Cintia Lopes; et al. “Whey Protein Modifies Gene Expression Related to Protein Metabolism Affecting Muscle Weight in Resistance-Exercised Rats”; Nutrition; July-August 2014. <http://www.ncbi.nlm.nih.gov/pubmed/24985006>

Jakubowicz, Daniela; Froy, Oren; et al. “Incretin, Insulinotropic and Glucose-Lowering Effects of Whey Protein Pre-Load in Type 2 Diabetes: A Randomised Clinical Trial”; Diabetologia; September 2014; published online July 10, 2014. <http://www.ncbi.nlm.nih.gov/pubmed/25005331>

Miller, Paige E.; Alexander, Dominik D.; and Perez, Vanessa. “Effects of Whey Protein and Resistance Exercise on Body Composition: A Meta-Analysis of Randomized Controlled Trials”; Journal of the American College of Nutrition; published online April 14, 2014. <http://www.ncbi.nlm.nih.gov/pubmed/24724774>




L-Leucine Benefits, Uses, Side Effects and Functions

Discover the Function, Sources and Benefits of the Health Supplement Ingredient L-Leucine or 2-Amino-4-Methylpentanoic Acid

Leucine – also known as L-leucine and by its scientific name, 2-amino-4-methylpentanoic acid – is a branched-chain amino acid (BCAA). Because the human body cannot synthesize this essential amino acid, it must be obtained from food sources such as meat, dairy products and legumes. L-leucine is also available in natural dietary supplements, including health and bodybuilding supplements such as Ana-GH, DBol-GH, Cut and Ripped Plus, Amino Shooter and Chocolate Whey Protein.

Functions of L-Leucine

Branched-chain amino acids like L-leucine stimulate protein synthesis by triggering pancreatic islet cells to release insulin. This protein synthesis primarily takes place in skeletal muscle, but also occurs to a lesser extent in the liver and adipose (fat) tissue. It is believed that L-leucine may help prevent or reduce muscle damage, enhance anabolic muscle signaling, lower blood-glucose levels and avoid faulty message transmission in the brain cells of people with certain diseases. It may also decrease serotonin production by blocking tryptophan transport to the brain, thereby reducing feelings of drowsiness and fatigue.

Sources of L-Leucine

According to the United States Department of Agriculture (USDA), common dietary sources of L-leucine include beef, pork, fish, chicken, turkey, eggs, cheese and milk. Legumes are another good source – particularly beans, soy and peanuts – as are nuts and seeds (such as almonds and sunflower seeds) and grains (like wheat germ, oats, corn and rice). L-leucine may also be consumed directly as part of a natural dietary supplement.

Leucine Benefits and Uses

Because of L-leucine’s role in protein synthesis, it is often used in health and bodybuilding supplements that are designed to build muscle strength, increase exercise endurance, reduce muscle breakdown and promote muscle recovery. Its ability to inhibit serotonin production means that L-leucine may help prevent or delay fatigue during exercise. L-leucine has also been shown to stimulate the appetite – making it useful for athletes looking to gain mass and weight.

In addition, L-leucine appears to benefit individuals with specific medical conditions. For example, it may help to lower blood-glucose levels in diabetics, and it can improve the health and nutrition of patients experiencing loss of appetite due to hemodialysis, cancer treatments or anorexia. L-leucine has also been shown to diminish symptoms in manic patients, reduce involuntary movements in individuals with tardive dyskinesia, and improve muscle control and brain function in patients with advanced liver disease, including various forms of hepatic encephalopathy.

Side Effects of L-Leucine and Potential Interactions

L-leucine is generally considered safe when taken in normal doses, such as those found in food and most dietary supplements. However, excessive amounts can result in hypoglycemia or vitamin B3 and B6 deficiencies. Users are advised to adhere to supplement dosing information and avoid consuming more than 39 grams of L-leucine per day.

Few L-leucine side effects have been recorded, though some users have reported experiencing fatigue or decreased motor coordination. Individuals with certain medical conditions – including amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease), isovaleric acidemia, branched-chain ketoaciduria (maple syrup urine disease) and chronic alcoholism – should avoid L-leucine, as it can pose health risks in these patients. In terms of L-leucine interactions, it appears to decrease the effectiveness of levodopa. Conversely, it can have an additive effect when taken with diabetes medication, potentially resulting in hypoglycemia. Other medications – such as Diazoxide and corticosteroids – can decrease the effects of L-leucine on protein, while thyroid hormone medication can cause the body to break down L-leucine more slowly.

More detailed safety information on L-leucine side effects and interactions can be found on WebMD. As with any medication or health supplement, it is best to consult your physician before taking dietary supplements containing L-leucine.

L-Leucine Research and Studies

Scientists have researched L-leucine and other BCAAs to determine their benefits and practical uses, and numerous studies have indicated a positive effect on muscle strength, exercise endurance and muscle recovery. An article published in the European Journal of Applied Physiology reported that outrigger canoeists using leucine supplements displayed significantly improved endurance performance and upper-body power. In Applied Physiology, Nutrition, and Metabolism, researchers noted that well-trained male cyclists who took a leucine-protein supplement after intense training subsequently exhibited improved high-intensity endurance performance and lower perceived levels of tiredness. And according to the Journal of Sports Science & Medicine, resistance-trained males who consumed an energy drink with leucine (and other key ingredients) prior to their workout demonstrated a significant increase in the number of repetitions successfully performed.

Other studies examined the impact of L-leucine on protein synthesis. Research findings published in The American Journal of Clinical Nutrition indicated that increasing the concentration of leucine in an essential amino acid supplement consumed during steady-state exercise resulted in a greater muscle protein synthesis response during recovery. And in The Journal of Nutrition, researchers determined that insulin and leucine work in synergy, allowing skeletal muscles to coordinate protein synthesis with physiological state and dietary intake.

For additional research related to L-leucine, refer to the PubMed site sponsored by the National Institutes of Health (NIH).

HGH.com Supplements With L-Leucine
Athletes, bodybuilders and fitness enthusiasts who wish to leverage the positive effects of L-leucine can find this essential amino acid in a variety of natural health and bodybuilding supplements from HGH.com:

Ana-GH – Each serving of Ana-GH contains 1.5 grams of L-leucine, which is blended with other branched-chain amino acids and active ingredients. This supplement is designed to jumpstart bulking cycles by promoting weight and mass gains while improving protein synthesis and contributing to joint and muscle repair.

Cut and Ripped Plus – Created to support cutting cycles and contest prep, Cut and Ripped Plus combines L-leucine with other active ingredients to help build muscle, increase strength and burn fat for a competition-ready physique. The capsules also help to boost energy and stamina, minimize pain, promote faster recovery and raise human growth hormone (HGH) levels.

DBol-GH – The proprietary blend of ingredients in DBol-GH includes L-leucine, which helps users to achieve lean mass and muscle growth, and also aids in muscle recovery. DBol-GH’s active ingredients are designed to stack and work together, delivering visible results and increasing HGH production.

Amino Shooter and Creatine Energy – Formulated to mix easily with cold water, Amino Shooter is used during intense workouts to protect and grow muscle. A single serving contains 3 grams of L-leucine, which supports protein synthesis and reduces muscle degradation.

Multi-Pro Chocolate Whey Protein – Each scoop of Multi-Pro Chocolate Whey provides 24 grams of protein and includes 2.16 grams of L-leucine. Fortified with vitamins and minerals, it provides a complete protein supplement for those looking to gain muscle and lose body fat.


References (Function, Sources, Benefits/Uses and Side Effects/Interactions):

Bruno, Gene. “A Primer on Branched Chain Amino Acids”; Smart Supplementation, published by Huntington College of Health Sciences; 2009. <http://www.hchs.edu/literature/BCAA.pdf>

Deuster, Patricia; Maier, Steven; et al. “Protein and Amino Acids Products – Branched Chain Amino Acids: Leucine, Isoleucine, Valine”; Dietary Supplements and Military Divers: A Synopsis for Undersea Medical Officers, published by Uniformed Services University of the Health Sciences; January 2004. <http://hprc-online.org/dietary-supplements/files/DietarySupplementUMO.pdf>

Memorial Sloan Kettering Cancer Center. “Leucine”; published under “About Herbs, Botanicals & Other Products” within Integrative Medicine area of website; last updated February 21, 2013. <http://www.mskcc.org/cancer-care/herb/leucine>

USDA Agricultural Research Service. “Leucine” search results in the National Nutrient Database for Standard Reference; accessed July 30, 2014. <http://ndb.nal.usda.gov/ndb/nutrients/index>

WebMD and Natural Medicines Comprehensive Database. “Branched Chain Amino Acids”; published under “Vitamins & Supplements”; accessed July 30, 2014. <http://www.webmd.com/vitamins-supplements/ingredientmono-1005-BRANCHED-CHAIN+AMINO+ACIDS.aspx?activeIngredientId=1005&activeIngredientName=BRANCHED-CHAIN+AMINO+ACIDS>

Research Sources:

Crowe, Melissa J.; Weatherson, Jarrad N.; and Bowden, Bruce F. “Effects of Dietary Leucine Supplementation on Exercise Performance”; European Journal of Applied Physiology; August 2006. <http://www.ncbi.nlm.nih.gov/pubmed/16265600>

Gonzalez, Adam M.; Walsh, Allyson L.; et al. “Effect of a Pre-Workout Energy Supplement on Acute Multi-Joint Resistance Exercise”; Journal of Sports Science & Medicine; June 2011. <http://www.ncbi.nlm.nih.gov/pubmed/24149870>

Norton, Layne E. and Layman, Donald K. “Branched-Chain Amino Acids in Exercise: Leucine Regulates Translation Initiation of Protein Synthesis in Skeletal Muscle after Exercise”; The Journal of Nutrition; February 2006. <http://www.ncbi.nlm.nih.gov/pubmed/16424142>

Pasiakos, Stefan M.; McClung, Holly L.; et al. “Leucine-Enriched Essential Amino Acid Supplementation During Moderate Steady State Exercise Enhances Postexercise Muscle Protein Synthesis”; The American Journal of Clinical Nutrition; September 2011. <http://www.ncbi.nlm.nih.gov/pubmed/21775557>

Thomson, Jasmine S.; Ali, Ajmol; and Rowlands, David S. “Leucine-Protein Supplemented Recovery Feeding Enhances Subsequent Cycling Performance in Well-Trained Men”; Applied Physiology, Nutrition, and Metabolism; April 2011. <http://www.ncbi.nlm.nih.gov/pubmed/21609286>




Anapolan Max - How The Ingredients in A-Max 50 Will Help You Build Muscle | An HGH.com Product Review

How The Ingredients of Anapolan Max (A-Max 50) by HGH.com Will Help You Gain Muscle

Anapolan Max - New Look, Same Great Formula!

 
 
Our #1 goal is delivering products that are safe, natural, and that work as advertised. Our product Anapolan Max, renamed for short "A-Max 50", has been a staple for muscle builders around the world for years. It's ingredients will help you rapidly grow muscle and for this reason, it's great for all types of bodybuilders.
 
Note - for other muscle builders and bodybuilding supplements, visit http://www.hgh.com.
 
Let's review the proprietary blend of ingredients for A-Max 50.
 
  • L-Tyrosine: This is a non-essential amino acid that that is an important building block for protein. It's reaction in your body helps create the neurotransmitter dopamine in your body, in addition to other hormones.  This amino acid is made in your body from phenylalanine. Because this ingredient helps in the production of dopamine, it also can have positive effects on focus and other mental and physical stimulations.
  • Shilajit: Known as "Blood of the mountain". Shilajit can boost fertility and increase testosterone levels. Ayurvedic healers even consider it to be an anti-aging substance, which can help balance HGH levels in your body. One of the main components of Shilajit is fulvic acid, which can clean the body of heavy metals, in turn causing testosterone levels and sperm count to rise. Researchers believe that Shilajit can reduce damage from free radicals in the testes and boost production of testosterone.
  • Tribulus: Proven to be effective for muscle building, the bodybuilding industry has looked to Tribulus for years. It's a flowering plant, originally native to warm climates, but now available throughout the world. In the 90's, Olympic weight lifting teams were quoted as using Tribulus to improve their performance. Tribulus can help improve performance by increasing testosterone levels, but it will also speed up the recovery of the muscles immediately following exercise. This is a great substance for helping protein synthesis for new muscles, helping repair and regrow new muscle tissue.
  • Mucuna Pruiens: Mucuna can be a great addition to any bodybuilders diet. It is rich in the amino acid L-Dopa, which helps lower cholesterol and blood sugar levels. It also increases the production of HGH in your body, which can increase your ability to build lean muscle and burn fat.
  • Epimedium: Also used as an ingredient for "herbal Viagra" supplements, Epimedium has great bone and muscle benefits. The components of Epimedium can help manage Cortisol levels in the blood. Cortisol levels directly affect body structures affecting bone and muscle deterioration. Thus, but managing Cortisol, Epimediums effect on the body will help prevent bone deterioration and will also cause an increase in muscle mass.
  • DHEA: DHEA is a natural hormone produced by your adrenal gland. Supplementing your DHEA can increase lean muscle mass and reduce body fat. DHEA is highest in your youth (mid 20's), and sharply declines over the years starting in your mid 30's. This ingredient is a highly talked about supplement and more studies are needed, but many bodybuilder experts will tell you that DHEA will promote lean muscle gains. Note, most athletic organizations ban DHEA due to its performance enhancing effects.
A-Max is currently available at http://www.hgh.com/anapolan-max.aspx. Buy two, get one free today!






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