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Somatotropin/Somatropin Benefits, Uses, Side Effects and Functions

Discover the Function, Sources and Benefits of Somatotropin Supplements and Somatropin Injections

Somatotropin—also known as human growth hormone (HGH) or simply as growth hormone (GH)—is a polypeptide produced by somatotrope cells in the pituitary gland. It supports skeletal growth in children and adolescents, and plays a role in metabolism, body composition, muscle growth and tissue repair in adults. In addition to the somatotropin naturally produced by the body, a synthetic form of HGH called somatropin is available with a doctor’s prescription. Certain health and bodybuilding supplements may also help increase somatotropin production through natural ingredients known as HGH releasers. Many of these ingredients can be found in the proprietary-blend formulas of Somatropinne HGH, Growth Factor Plus, HGH 30,000 Nanograms, A-MAX 50, and HGF MAX, among others.

Functions of Somatotropin

Children and adolescents require somatotropin for proper growth and development; those with an HGH deficiency may require somatropin injections to achieve normal height. In adults, somatotropin helps maintain healthy tissues and organs. It can also increase bone density, muscle mass, and protein synthesis as well as decrease body fat and improve exercise capacity. Because HGH production naturally declines with age, some adults take somatotropin-boosting supplements to enhance their athletic performance and combat the physical signs of aging.

Sources of Somatotropin/Somatropin

For most individuals, the primary source of somatotropin is the body’s endogenous production by the somatotropic cells of the pituitary gland. The body produces its highest levels of somatotropin during childhood and adolescence; these levels significantly decline when the individual reaches full adult height. Scientists have also developed a synthetic form of somatotropin known as somatropin or somatrem, using E. coli or mammalian cells to create therapeutic proteins in a laboratory setting. Somatropin is chemically identical to the somatotropin that is produced by the pituitary gland and administered by subcutaneous injection. It is a regulated substance, which means it can only be legally prescribed for FDA-approved uses.

Since somatropin injections are not legally available to healthy adults, those seeking the benefits of somatotropin may opt to take natural supplements that are designed to boost the body’s own HGH production. Certain amino acids are recognized as natural HGH releasers—including GABA, arginine, ornithine, glutamine, lysine, tyrosine and glycine—so dietary supplements containing these ingredients may help increase somatotropin levels.

Somatropin Benefits and Uses

The pituitary gland’s secretion of somatotropin supports bodily growth and development throughout childhood and adolescence, so the most common reason for prescribing somatropin is to treat children and teens with HGH deficiency or specific medical conditions. FDA-approved pediatric uses of somatropin include idiopathic growth hormone deficiency, Noonan syndrome, Turner syndrome, Prader-Willi syndrome, chronic renal insufficiency, short stature homeobox-containing gene (SHOX) deficiency, and idiopathic short stature.

Although HGH levels naturally decline with age, somatotropin continues to play a role throughout adulthood—helping to regulate metabolism and protein synthesis and promoting organ, tissue and bone health. Somatropin may be legally prescribed to adults who have severe HGH deficiency, which normally occurs due to a pituitary adenoma (tumor) or adenoma-related surgery or radiation treatments. It is also sometimes prescribed to prevent or minimize wasting in AIDS patients.

Somatropin injections can improve bone density, muscle mass and exercise capacity in adults with HGH deficiency, and they can produce similar outcomes in healthy adults. As a result, some bodybuilders and athletes take somatropin to enhance their athletic performance and physique. However, it should be noted that somatropin cannot legally be prescribed for such purposes. Furthermore, the World Anti-Doping Agency (WADA), International Olympic Committee and numerous sports organizations have banned the use of HGH injections among athletes.

Given the potential repercussions associated with illegal somatropin injections, many bodybuilders, athletes and aging adults have starting taking natural HGH supplements to help the body increase its own somatotropin production. Proponents of somatotropin-boosting supplements report that these natural HGH releasers have helped them develop lean muscle, improve their strength and endurance, and recover from intense workouts and injuries more quickly. They also credit HGH supplements with enhancing their body composition and slowing the visible signs of aging.

Somatropin Side Effects

Individuals considering HGH injections should be aware of somatropin side effects and interactions. Some users have experienced an allergic reaction, with symptoms such as itching or rashes, chest pain, difficulty breathing, or swelling of the face, tongue, or throat. Other possible side effects include headaches, nausea, vomiting, blurred vision, fluid retention, swelling of the hands or feet, muscle stiffness or pain, and burning, tingling or numbness in the skin. Somatropin may increase the risk of developing diabetes, cancer or pancreatitis, and it can cause dislocation of the hipbone that results in limping or knee/hip pain. Interactions have been recorded when somatropin is used with estrogen hormone replacement or glucocorticoids (such as prednisone or hydrocortisone), and somatropin can cause adverse effects in patients with diabetes, scoliosis, kidney disease and certain other medical conditions.

Somatotropin-boosting HGH supplements tend to have fewer and less severe side effects than somatropin injections; however, the side effects and interactions will vary depending on the supplement’s ingredients.

More detailed safety information on somatropin side effects, interactions and precautions can be found on the Mayo Clinic website. For natural somatotropin-boosting supplements, refer to the relevant ingredient articles on HGH.com to learn about potential side effects and interactions. As with any medication or health supplement, it is best to consult your physician before using somatropin injections or natural HGH supplements.

Somatotropin/Somatropin Research and Studies

Researchers have conducted numerous studies on both the natural and synthetic forms of somatotropin. Visit the PubMed site sponsored by the National Institutes of Health (NIH) to explore the latest somatotropin research and somatropin studies. For research on specific ingredients that have been shown to boost somatotropin levels, refer to the corresponding ingredient articles on the HGH.com blog.

You will discover there is a wealth of information on at HGH.com. We recently posted this related blog post on HGH/somatotropin: Human Growth Hormone (HGH) Benefits, Uses, Side Effects and Functions.

HGH.com Supplements With Natural Somatotropin/HGH Releasers

Many of the health and bodybuilding supplements available from HGH.com are formulated to naturally increase somatotropin/HGH levels. These products include:

Somatropinne HGH – Purity Select’s natural Somatropinne HGH capsules contain a proprietary blend of L-arginine, cowhage, maca and horny goat weed. As an over-the-counter somatotropin releaser, this supplement is formulated to help athletes gain lean muscle and increased energy while also providing weight-loss and anti-aging benefits.

HGH 30,000 Nanograms Pills and HGH 30,000 Nanograms Spray –Purity Select’s 30,000 Nanogram HGH pills and spray are designed to promote somatotropin production, muscle growth, increased energy and other health benefits. They contain a powerful combination of amino acids—including L-glutamine, L-arginine, L-ornithine, L-lysine, L-glycine, L-valine and L-tyrosine —as well as other natural ingredients such as colostrum, GABA, cowhage (mucuna pruriens), long jack and deer antler velvet.

Growth Factor Plus – As its name suggests, Growth Factor Plus is intended to support height growth as well as bone and joint health. Its proprietary blend of ingredients features amino acids such as L-arginine, L-ornithine, L-lysine, L-glycine, L-glutamine, and L-tyrosine.

HGF MAX – Purity Select HGF MAX is intended to boost somatotropin production, improve muscle tone, build muscle, promote fat loss, boost energy and increase metabolism. Its proprietary blend of ingredients includes arginine, GABA, glutamine, lysine, glycine, tyrosine, ornithine and deer antler velvet.

Ana-GH – These capsules contain a blend of L-group amino acids such as L-leucine and L-valine as well as plant-based ingredients such as horny goat weed and maca. Ana-GH is intended to jumpstart bulking cycles by promoting muscle mass and weight gains, improving protein synthesis, and contributing to joint and muscle repair.

Anapolan-MAX 50 (A-MAX 50) – Anapolan-MAX is formulated to support lean muscle gain while boosting somatotropin production and testosterone levels. Its proprietary blend of ingredients includes L-tyrosine, Tribulus terrestris, cowhage (mucuna pruriens), shilajit and dehydroepiandrosterone.

ClenXDV – Featuring a proprietary blend of DHEA, deer antler velvet, wild yam, Tribulus terrestris and other natural ingredients, ClenXDV is intended to help athletes and bodybuilders build muscle, lose weight and burn fat.

DBol-GH – This anabolic lean muscle gainer is designed to promote lean mass and muscle growth, support muscle recovery and naturally boost HGH levels with a proprietary blend of ingredients that include bovine colostrum, beta-ecdysterone, L-valine and L-leucine.

Dekka – With a blend of Korean ginseng root, yucca bark, wild yam root, and dehydroepiandrosterone, Dekka capsules are formulated to help bodybuilders achieve lean mass, weight gain, muscle building and bulking.

Testosterone Plus – HGH Testosterone Plus features a proprietary blend of long jack, maca, Tribulus terrestris, ginkgo biloba and other natural ingredients that are intended to help build muscle, aid in muscle recovery and boost energy while offering sexual health benefits such as improved libido and stamina.

RoidX Juice – The ingredients in RoidX Juice are designed to help bodybuilders quickly develop muscle and gain weight in addition to supporting muscle recovery. RoidX Juice capsules contain a proprietary blend of Vitamin E, Tribulus terrestris, shilajit and dehydroepiandrosterone.

Winstrol Max – Optimized for cutting cycles, Winstrol Max is formulated to promote lean mass gain and help athletes achieve ripped abs. Its powerful blend of ingredients includes L-group amino acids such as leucine, arginine and valine as well as oat straw (Avena sativa) extract and saw palmetto.

References:

Drug Enforcement Administration. “Human Growth Hormone”; DEA fact sheet; August 2013. <http://www.deadiversion.usdoj.gov/drug_chem_info/hgh.pdf>

U.S. Food and Drug Administration (FDA). “Somatropin Information”; published under “Drug Safety and Availability”; August 4, 2011. <http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm237839.htm>

Kamionka, Mariusz. “Engineering of Therapeutic Proteins Production in Escherichia Coli”; Current Pharmaceutical Biotechnology; February 2011. <http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179032>

Mayo Clinic. “Somatropin, E-Coli Derived (Subcutaneous Route, Injection Route)”; Mayo Clinic website; last updated April 1, 2015. <http://www.mayoclinic.org/drugs-supplements/somatropin-e-coli-derived-subcutaneous-route-injection-route/description/drg-20071575>

Mayo Clinic. “Somatropin, Mammalian Derived (Injection Route, Subcutaneous Route)”; Mayo Clinic website; last updated April 1, 2015. <http://www.mayoclinic.org/drugs-supplements/somatropin-mammalian-derived-injection-route-subcutaneous-route/description/drg-20071668>

WebMD. “Somatropin Injection”; accessed June 9, 2015. <http://www.webmd.com/drugs/2/drug-6259/somatropin-injection/details>





Human Growth Hormone (HGH) Benefits, Uses, Side Effects and Functions

Discover the Function, Sources and Benefits of Human Growth Hormone, or HGH, Supplements

Human growth hormone (HGH)—also known as somatotropin or simply as growth hormone (GH)—is a polypeptide hormone that is produced by the pituitary gland. It promotes growth in children and adolescents, and plays a role in body composition, metabolism, muscle growth and tissue repair in adults. Beyond the human growth hormones naturally produced by the body, synthetic HGH—or recombinant HGH—is manufactured in laboratories and may be obtained with a doctor’s prescription. Select health and bodybuilding supplements may also help boost human growth hormone levels with natural ingredients known as HGH releasers or HGH secretagogues. Many of these ingredients can be found in products such as HGH 30,000 Nanograms, Somatropinne HGH, Ana-GH, DBol-GH and Growth Factor Plus, among others.

Functions of Human Growth Hormone

HGH is required to support proper growth and development in children and adolescents, and it also plays a role in adult metabolism. Human growth hormone can help increase muscle mass, bone density, exercise capacity and protein synthesis, and may decrease body fat. It also helps maintain healthy tissues and organs. Since human growth hormone production naturally declines with age, many believe that HGH supplementation can help improve athletic performance and provide anti-aging benefits in adults.

Sources of HGH

As previously noted, the primary source of human growth hormone is the pituitary gland. HGH production peaks during childhood and adolescence, and substantially declines once full adult height is attained. Laboratory-manufactured synthetic HGH—also known as recombinant HGH, somatropin or somatrem—is another source of growth hormone available to some individuals. This injectable form of HGH may be prescribed to children and some adults that have been diagnosed with human growth hormone deficiency or specific medical conditions. Synthetic HGH is a regulated substance and may only legally be prescribed for FDA-approved uses. These include Turner’s syndrome, Prader-Willi syndrome, chronic renal insufficiency and idiopathic short stature in children, as well as HGH deficiency and AIDS-related wasting in adults.

Since recombinant HGH is not legally available to healthy adults, many individuals rely on natural HGH supplements that are formulated to increase their body’s own production of human growth hormone. A number of amino acids are recognized as natural HGH releasers. These include L-arginine, L-glutamine, L-glycine, L-lysine, L-ornithine, L-tyrosine and GABA.

Human Growth Hormone Benefits and Uses

The main purpose of HGH is to support human growth and development during childhood and adolescence, and this is the most common reason synthetic HGH is prescribed to young patients. However, human growth hormone continues to play a role throughout adulthood; it helps to regulate metabolism and protein synthesis and supports bone, tissue and organ health. Recombinant HGH may be legally prescribed to adults who have severe HGH deficiency, which typically results from a pituitary adenoma (tumor) or treatment of an adenoma with surgery or radiotherapy. Synthetic growth hormone is also sometimes prescribed to treat the wasting syndrome that can occur in individuals with AIDS.

Human growth hormone injections can increase muscle mass, bone density and exercise capacity in adults with HGH deficiency, and it can produce similar effects in healthy adults. For this reason, some athletes and bodybuilders take recombinant HGH to improve their physique and athletic performance, even though it cannot legally be prescribed for such purposes and is banned by the World Anti-Doping Agency (WADA), International Olympic Committee and numerous sports organizations.

In light of the controversy and legal restrictions surrounding injectable HGH, a growing number of athletes, bodybuilders and aging adults have turned to natural HGH supplements to help boost the pituitary gland’s secretion of human growth hormone. Many report that L-group amino acids and other natural HGH releasers have helped them build lean muscle, enhance bodily strength, increase athletic endurance, tone their physique, recover faster from intense workouts and injuries, and minimize or reverse the visible signs of aging.

HGH Side Effects

Synthetic human growth hormone injections are associated with a number of side effects that can range widely in severity. Among the more serious HGH side effects some patients have experienced are atherosclerosis (hardening of the arteries), hypertension (high blood pressure), and abnormal growth of bones and internal organs such as the heart, kidneys, and liver. HGH may also increase the risk of developing diabetes and can cause cancerous tumors to grow in size. Other human growth hormone side effects include: edema (swelling caused by excess fluid in tissues); carpal tunnel syndrome; joint, muscle or nerve pain; numbness or tingling sensations in the skin; headaches; dizziness; blurred vision; chest pain; irregular heartbeat; and a rash or itching near the injection site.

Natural HGH supplements tend to have fewer and less severe side effects than synthetic growth hormone injections; however, the side effects and interactions will vary depending on the ingredients.

More detailed safety information on synthetic HGH side effects can be found on the Mayo Clinic website under the “Growth Hormone (Parenteral Route)” entry. For natural HGH supplements, refer to the relevant supplement ingredient articles on HGH.com to learn about potential side effects and interactions. As with any medication or health supplement, it is best to consult your physician before using synthetic human growth hormone injections or HGH supplements.

HGH Research and Studies

A wide body of research exists on human growth hormones, including naturally produced HGH, recombinant HGH and ingredients that function as HGH releasers. Refer to the PubMed site sponsored by the National Institutes of Health (NIH) for an overview of the latest HGH research or to search for articles highlighting the results of human growth hormone studies. For research on specific ingredients that function as HGH releasers, refer to the relevant ingredient articles on the HGH.com blog.

HGH.com Supplements With Natural HGH Releasers

Many of the health and bodybuilding supplements available from HGH.com are formulated to naturally increase HGH levels. These products include:

HGH Pills and HGH Spray – Available as HGH pills or an oral spray, Purity Select’s 30,000 Nanogram products are designed to promote human growth hormone production, muscle growth, increased energy and other health benefits. They contain a powerful combination of L-group amino acids—including L-arginine, L-glutamine, L-glycine, L-lysine, L-ornithine, L-tyrosine and L-valine—and other natural ingredients, such as colostrum, cowhage (mucuna pruriens), deer antler velvet, GABA and long jack.

Growth Factor Plus – As its name implies, Growth Factor Plus is intended to promote height growth while also supporting bone and joint health. Its proprietary blend of ingredients features L-group amino acids such as L-arginine, L-glutamine, L-glycine, L-lysine, L-ornithine and L-tyrosine.

Somatropinne HGH – Purity Select’s natural Somatropinne HGH capsules contain a proprietary blend of plant extracts, including maca, cowhage and horny goat weed as well as L-arginine. As an over-the-counter HGH releaser, this supplement is formulated to help athletes gain lean muscle and increased energy while also providing weight-loss and anti-aging benefits.

HGF MAX – Purity Select HGF MAX is intended to boost HGH production, improve muscle tone, build muscle, promote fat loss, boost energy and increase metabolism. Its proprietary blend of ingredients includes GABA, L-arginine, L-glutamine, L-glycine, L-lysine, L-ornithine, L-tyrosine and deer antler velvet.

Ana-GH – Each serving of Ana-GH contains L-group amino acids such as L-leucine and L-valine as well as other natural ingredients, including maca and horny goat weed. This supplement is intended to jumpstart bulking cycles by promoting muscle mass and weight gains, improving protein synthesis, and contributing to joint and muscle repair.

Anapolan-MAX 50 (A-MAX 50) – Anapolan MAX is formulated to support lean muscle gain while boosting HGH production and testosterone levels. Its proprietary blend of ingredients includes L-tyrosine, shilajit, Tribulus terrestris, cowhage (mucuna pruriens) and dehydroepiandrosterone.

ClenXDV – Featuring a proprietary blend of Tribulus terrestris, wild yam, deer antler velvet, DHEA and other natural ingredients, ClenXDV is intended to help athletes and bodybuilders build muscle, lose weight and burn fat.

DBol-GH – This anabolic lean muscle gainer is designed to promote lean mass and muscle growth, support muscle recovery and naturally boost HGH levels with a proprietary blend of ingredients that include beta-ecdysterone, L-leucine, L-valine and bovine colostrum.

Dekka – With a blend of wild yam root, yucca bark, Korean ginseng root and dehydroepiandrosterone, these capsules are formulated to help bodybuilders achieve weight gain, lean mass, bulking and muscle building.

Testosterone Plus – HGH Testosterone Plus features a proprietary blend of maca, long jack, ginkgo biloba, Tribulus terrestris and other natural ingredients that are intended to help build muscle, aid in muscle recovery and boost energy while offering sexual health benefits such as improved libido and stamina.

RoidX Juice – The ingredients in RoidX Juice are designed to help bodybuilders quickly gain muscle and weight while supporting muscle recovery. RoidX Juice capsules contain a proprietary blend of shilajit, Tribulus terrestris, Vitamin E and dehydroepiandrosterone.

Winstrol Max – Optimized for cutting cycles, Winstrol Max is formulated to promote lean mass gain and help athletes achieve ripped abs. Its powerful blend of ingredients includes L-group amino acids such as L-arginine, L-leucine and L-valine as well as saw palmetto and oat straw (Avena sativa) extract.

References:

Drug Enforcement Administration. “Human Growth Hormone”; DEA fact sheet; August 2013. <http://www.deadiversion.usdoj.gov/drug_chem_info/hgh.pdf>

Dunkin, Mary Anne. “Human Growth Hormone (HGH)”; WebMD; December 30, 2014. <http://www.webmd.com/fitness-exercise/human-growth-hormone-hgh>

Fordyce, Tom. “Human Growth Hormone Explained”; BBC Sport; July 27, 2003. <http://news.bbc.co.uk/sport2/hi/front_page/3101343.stm>

Jackson, Joe. “Unlock Your Potential: How to Boost Your HGH Levels”; Men’s Fitness; accessed June 5, 2015. <http://www.mensfitness.com/nutrition/supplements/unlock-your-potential-how-to-boost-your-hgh-levels>

Mayo Clinic. “Drugs and Supplements: Growth Hormone (Parenteral Route)”; May Clinic website; last updated April, 2015. <http://www.mayoclinic.org/drugs-supplements/growth-hormone-parenteral-route/description/drg-20069416>

Mayo Clinic Staff. “Human Growth Hormone: Does It Slow Aging?”; Mayo Clinic website; February 1, 2014. <http://www.mayoclinic.org/healthy-lifestyle/healthy-aging/in-depth/growth-hormone/art-20045735>

Mayo Clinic Staff. “Performance-Enhancing Drugs: Know the Risks”; Mayo Clinic website; December 12, 2012. <http://www.mayoclinic.org/healthy-lifestyle/fitness/in-depth/performance-enhancing-drugs/art-20046134>




Bovine Colostrum Benefits, Uses, Side Effects and Functions

Discover the Function, Sources and Benefits of the Health Supplement Ingredient Bovine Colostrum

Bovine colostrum – also known as bovine immunoglobulin or simply as colostrum – is a milky fluid secreted by a cow’s mammary glands in the first few days after calving, prior to full lactation. Colostrum is also produced by humans and other mammals; however, the primary source of colostrum in dietary supplements is cattle. It contains a number of beneficial substances, including immunoglobulins, lactoferrin, proline-rich polypeptides, cytokines, growth factors, and other vitamins and minerals. Adults can obtain the benefits of colostrum through natural health and bodybuilding supplements such as HGH 30,000 Nanograms pills, DBol-GH, Growth Factor Plus and protein shake mixes.

Functions of Colostrum

The nutrients, antibodies and growth factors contained in colostrum contribute to the health and development of newborns. Similarly, these substances can have beneficial effects for adults when colostrum extract is consumed via dietary supplements. Immunoglobulin and lactoferrin have antiviral and antibacterial properties that support immune system function, while proline-rich polypeptides (PRPs) and cytokines help regulate immune system activity. Furthermore, the cytokines and growth factors in colostrum appear to enhance the protective and repair capabilities of the gastrointestinal (GI) tract. Colostrum’s growth factors are also believed to improve athletic performance, increase lean body mass, and accelerate muscle recovery and repair.

Sources of Colostrum

Female mammals secrete colostrum from their mammary glands following the birth of a newborn, before full lactation occurs. Infants consume colostrum during their first few days of nursing. Adults generally obtain colostrum through health supplements that contain bovine colostrum – the extract of a cow’s first milk.

Bovine Colostrum Benefits and Uses

Evidence suggests that the health benefits of bovine colostrum include supporting and stimulating immune system function, preventing infections, providing GI protection, treating diarrhea and colitis, and accelerating healing. Bovine colostrum is also used as an ingredient in human growth hormone (HGH) releasers and bodybuilding supplements, as the naturally occurring growth hormones in colostrum are believed to enhance athletic performance, improve body composition, and promote faster recovery from injuries and intense workouts. These performance-related benefits derive from the growth hormones’ ability to help increase lean muscle mass, metabolize fat for fuel, improve stamina, and stimulate cell and tissue growth.

Side Effects of Bovine Colostrum and Potential Interactions

Dietary supplements containing bovine colostrum are generally considered safe for healthy adults, as few side effects have been reported. However, individuals who are allergic to cow’s milk may also have an allergic reaction to bovine colostrum. There have been rare reports of side effects in HIV-positive patients, such as nausea and vomiting. Colostrum may contain high levels of naturally occurring estrogen, so patients with hormone-sensitive cancer should avoid it. There are no known interactions of bovine colostrum with medications. Information on bovine colostrum contraindications is provided on the Memorial Sloan Kettering Cancer Center website, while details on colostrum side effects can be found on WebMD. As with any medication or health supplement, it is best to consult your physician before taking dietary supplements containing bovine colostrum.

Colostrum Research and Studies

Considerable research has been conducted on the effects of bovine colostrum, particularly in relation to its health benefits and impact on athletic performance. Scholarly articles published in Human Vaccines & Immunotherapeutics, the Alternative Medicine Review and the British Journal of Nutrition explored the clinical uses of bovine colostrum and reported that hyperimmune bovine colostrum has been proven effective in treating diarrhea caused by rotavirus, E. Coli, cryptosporidium, shigellosis, C. difficile infection (CDI) and other GI infections.

In terms of athletic performance, body composition, and healing and recovery, numerous studies suggest that bovine colostrum can have positive effects. In the Journal of Applied Physiology, European researchers asserted that bovine colstrum has the ability to naturally increase levels of insulin-like growth factor 1 (IGF-1), which may promote protein synthesis. A review of studies published in Sports Medicine cited evidence suggesting that bovine colostrum supplementation is most effective during periods of high-intensity training and recovery from high-intensity training, producing improved intramuscular buffering capacity and increases in lean body mass. In the Australian Journal of Science and Medicine in Sport, researchers noted that bovine colostrum improves recovery time. Scientists reported in Nutrition that when bovine colostrum is combined with exercise, it may increase bone-free lean body mass in active men and women. And in the International Journal of Sport Nutrition and Exercise Metabolism, researchers stated that colostrum supplementation helped improve leg-press and upper-body strength and generated increases in muscle thickness, lean tissue mass and cognitive function in older adults during resistance training.

For additional bovine colostrum research, refer to the PubMed site sponsored by the National Institutes of Health (NIH).

HGH.com Supplements Containing Bovine Colostrum

Bodybuilders, athletes and fitness enthusiasts can reap the health benefits of bovine colostrum with these natural HGH releasers and bodybuilding supplements from HGH.com:

HGH 30,000 Nanograms Pills – Bovine colostrum is featured in the proprietary blend of ingredients in HGH 30,000 Nanograms capsules. These oral supplements are formulated to naturally boost HGH production while supporting muscle growth and recovery, enhanced muscle conditioning, increased strength and stamina, anti-aging effects and other benefits.

DBol-GH – With a proprietary blend of bovine colostrum and other active ingredients, DBol-GH is designed to help users achieve lean mass and muscle growth as well as anabolic muscle building. It also aids in muscle recovery during intense bodybuilding training. The ingredients are designed to stack and work together, delivering visible results and boosting HGH levels.

Growth Factor Plus – The active ingredients in Growth Factor Plus include L-group amino acids, soy protein isolate and 50mg of colostrum. This powerful combination is intended to increase bone density, improve bone and joint strength, and contribute to a measurable growth in height.

CytoSport EvoPro Berry – Each scoop of EvoPro Berry shake mix contains purified bovine colostrum extract and 26 grams of protein. The formula is more complete than whey, yet has very little fat or carbohydrates. This product has the potential to increase lean muscle mass, stimulate growth receptors and sustain an anabolic state for enhanced protein synthesis.

Mega Shake Strawberry – Blending colostrum extract with other powerful active ingredients, Mega Shake provides 32 grams of total protein per serving. It is formulated to help increase muscle tone, reduce body fat, provide energy, and support muscle growth and repair.

References (Function, Sources, Benefits/Uses and Side Effects/Interactions):

Memorial Sloan Kettering Cancer Center. “Bovine Colostrum”; published under “About Herbs, Botanicals & Other Products” within Integrative Medicine area of website; last updated April 29, 2013; accessed November 5, 2014. <http://www.mskcc.org/cancer-care/herb/bovine-colostrum>

Deuster, Patricia; Maier, Steven; et al. “Protein and Amino Acids Producers: Colostrum Protein”; Dietary Supplements and Military Divers: A Synopsis for Undersea Medical Officers, published by Uniformed Services University of the Health Sciences; January 2004. <http://hprc-online.org/dietary-supplements/files/DietarySupplementUMO.pdf>

Bruno, Gene. “Colostrum”; Smart Supplementation, published by Huntington College of Health Sciences; 2005. <http://www.hchs.edu/literature/colostrum.pdf>

WebMD and Natural Medicines Comprehensive Database. “Colostrum”; published under “Vitamins & Supplements”; accessed November 5, 2014. <http://www.webmd.com/vitamins-supplements/ingredientmono-785-COLOSTRUM.aspx?activeIngredientId=785&activeIngredientName=COLOSTRUM&source=3>

Research Sources:

Antonio, Jose; Sanders, Michael S.; and Van Gammeren, Darin. “The Effects of Bovine Colostrum Supplementation on Body Composition and Exercise Performance in Active Men and Women”; Nutrition; March 2001. <http://www.ncbi.nlm.nih.gov/pubmed/11312068>

Buckley JD, Abbott MJ, Brinkworth GD, Whyte PB. “Bovine Colostrum Supplementation During
Endurance Running Training Improves Recovery, But Not Performance”; Journal of Science and Medicine in Sport; June 2002. <http://www.ncbi.nlm.nih.gov/pubmed/12188088>

Duff, Whitney R.D.; Chilibeck, Philip D.; et al. “The Effect of Bovine Colostrum Supplementation in Older Adults During Resistance Training”; International Journal of Sport Nutrition and Exercise Metabolism; June 2014. <http://www.ncbi.nlm.nih.gov/pubmed/24281841>

Kelly, Gregory S. “Bovine Colostrums: A Review of Clinical Uses”; Alternative Medicine Review; November 2003. <http://www.ncbi.nlm.nih.gov/pubmed/14653766>

Korhonen, Hannu; Marnila, Pertti; and Gill, Harsharnjit S. “Bovine Milk Antibodies for Health”; British Journal of Nutrition; November 2000. <http://www.ncbi.nlm.nih.gov/pubmed/11242458>

Mero, Antti; Kähkönen, Jonne; et al. “IGF-I, IgA, and IgG Responses to Bovine Colostrum Supplementation During Training”; Journal of Applied Physiology; August 2002. <http://www.ncbi.nlm.nih.gov/pubmed/12133885>

Mitra, Amal K.; Mahalanabis, Dilip; et al. “Hyperimmune Cow Colostrum Reduces Diarrhoea Due to Rotavirus: A Double-Blind, Controlled Clinical Trial”; Acta Paediatrica; September 1995. <http://www.ncbi.nlm.nih.gov/pubmed/8652974>

Shing, Cecilia M.; Hunter, Denise C.; and Stevenson, Lesley M. “Bovine Colostrum Supplementation and Exercise Performance: Potential Mechanisms”; Sports Medicine; December 2009. <http://www.ncbi.nlm.nih.gov/pubmed/19902984>

Steele, Jennifer; Sponseller, Jerlyn; et al. “Hyperimmune Bovine Colostrum for Treatment of GI Infections: A Review and Update on Clostridium Difficile”; Human Vaccines & Immunotherapeutics; July 2013. <http://www.ncbi.nlm.nih.gov/pubmed/23435084>





November 2014 Tips from IFBB Pros Presented by HGH.com

HGH.com Presents IFBB Pros & Tips: November 2014 Edition

Get some quick tips and sage advice from some of the most incredible IFBB professionals. For the October 2014 edition of HGH.com’s Tips from IFBB Pros, we bring out the big guns with a quick tip from Steve Kuclo, as well as interviews with the world’s top IFBB bikini and fitness models. Plus, we get to see what life is like for IFBB Pro Karina Nascimento and we’ve added some awesome pins to our dedicated IFBB Pros & Tips Pinterest board to inspire and motivate you.

IFBB Pro Steve Kuclo’s Quick Tip

What’s the correct technique for doing a seated rear delt lateral raise? IFBB Pro Steve Kuclo provides demonstration for completing this bodybuilding rear delt exercise. As one of the main muscle groups that really pops when you’re on stage at a bodybuilding competition, the rear delts can also be well built by doing rear delt lateral raise. All you need is a couple of dumbbells, a flat bench and Steve Kuclo's know-how. Steve also shares whether you should use low, medium or high weight for the best results.

Advice from the World’s Top IFBB Bikini and Fitness Models

Let’s hear the top tips from the world’s best bikini and fitness models. They claim that, "anyone can do it!" When it comes to training, nutrition, taking the proper supplements, and having a personal trainer that cares about your health, consistency is key to get the most incredible results. Remember, it's not just a physical challenge, but it's a mental challenge as well. These IFBB leading ladies also share insight regarding setting goals, staying healthy and fit, and how to prepare for competition.

What's Life Like for IFBB Pro Karina Nascimento

Spend the day with IFBB Pro Karina Nascimento. From a radio show to working out to a photo shoot and more, we get to see how Karina spends her time two days before the New York Pro. Plus, check out what she’s eating and take a look at Karina on stage for the competition. Will she cave for what she craves?

More IFBB Pros & Tips on Pinterest

We’ve added more tips and tricks from the IFBB Pros on Pinterest. Make sure to take a look at this totally awesome Pinterest board filled with inspiration, perspiration and nutrition-related pins from IFBB pros. Stop back by often as we'll continue to update this board.

Follow Bodybuilding's IFBB Pros & Tips Pinterest board.

 




L-Leucine Benefits, Uses, Side Effects and Functions

Discover the Function, Sources and Benefits of the Health Supplement Ingredient L-Leucine or 2-Amino-4-Methylpentanoic Acid

Leucine – also known as L-leucine and by its scientific name, 2-amino-4-methylpentanoic acid – is a branched-chain amino acid (BCAA). Because the human body cannot synthesize this essential amino acid, it must be obtained from food sources such as meat, dairy products and legumes. L-leucine is also available in natural dietary supplements, including health and bodybuilding supplements such as Ana-GH, DBol-GH, Cut and Ripped Plus, Amino Shooter and Chocolate Whey Protein.

Functions of L-Leucine

Branched-chain amino acids like L-leucine stimulate protein synthesis by triggering pancreatic islet cells to release insulin. This protein synthesis primarily takes place in skeletal muscle, but also occurs to a lesser extent in the liver and adipose (fat) tissue. It is believed that L-leucine may help prevent or reduce muscle damage, enhance anabolic muscle signaling, lower blood-glucose levels and avoid faulty message transmission in the brain cells of people with certain diseases. It may also decrease serotonin production by blocking tryptophan transport to the brain, thereby reducing feelings of drowsiness and fatigue.

Sources of L-Leucine

According to the United States Department of Agriculture (USDA), common dietary sources of L-leucine include beef, pork, fish, chicken, turkey, eggs, cheese and milk. Legumes are another good source – particularly beans, soy and peanuts – as are nuts and seeds (such as almonds and sunflower seeds) and grains (like wheat germ, oats, corn and rice). L-leucine may also be consumed directly as part of a natural dietary supplement.

Leucine Benefits and Uses

Because of L-leucine’s role in protein synthesis, it is often used in health and bodybuilding supplements that are designed to build muscle strength, increase exercise endurance, reduce muscle breakdown and promote muscle recovery. Its ability to inhibit serotonin production means that L-leucine may help prevent or delay fatigue during exercise. L-leucine has also been shown to stimulate the appetite – making it useful for athletes looking to gain mass and weight.

In addition, L-leucine appears to benefit individuals with specific medical conditions. For example, it may help to lower blood-glucose levels in diabetics, and it can improve the health and nutrition of patients experiencing loss of appetite due to hemodialysis, cancer treatments or anorexia. L-leucine has also been shown to diminish symptoms in manic patients, reduce involuntary movements in individuals with tardive dyskinesia, and improve muscle control and brain function in patients with advanced liver disease, including various forms of hepatic encephalopathy.

Side Effects of L-Leucine and Potential Interactions

L-leucine is generally considered safe when taken in normal doses, such as those found in food and most dietary supplements. However, excessive amounts can result in hypoglycemia or vitamin B3 and B6 deficiencies. Users are advised to adhere to supplement dosing information and avoid consuming more than 39 grams of L-leucine per day.

Few L-leucine side effects have been recorded, though some users have reported experiencing fatigue or decreased motor coordination. Individuals with certain medical conditions – including amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease), isovaleric acidemia, branched-chain ketoaciduria (maple syrup urine disease) and chronic alcoholism – should avoid L-leucine, as it can pose health risks in these patients. In terms of L-leucine interactions, it appears to decrease the effectiveness of levodopa. Conversely, it can have an additive effect when taken with diabetes medication, potentially resulting in hypoglycemia. Other medications – such as Diazoxide and corticosteroids – can decrease the effects of L-leucine on protein, while thyroid hormone medication can cause the body to break down L-leucine more slowly.

More detailed safety information on L-leucine side effects and interactions can be found on WebMD. As with any medication or health supplement, it is best to consult your physician before taking dietary supplements containing L-leucine.

L-Leucine Research and Studies

Scientists have researched L-leucine and other BCAAs to determine their benefits and practical uses, and numerous studies have indicated a positive effect on muscle strength, exercise endurance and muscle recovery. An article published in the European Journal of Applied Physiology reported that outrigger canoeists using leucine supplements displayed significantly improved endurance performance and upper-body power. In Applied Physiology, Nutrition, and Metabolism, researchers noted that well-trained male cyclists who took a leucine-protein supplement after intense training subsequently exhibited improved high-intensity endurance performance and lower perceived levels of tiredness. And according to the Journal of Sports Science & Medicine, resistance-trained males who consumed an energy drink with leucine (and other key ingredients) prior to their workout demonstrated a significant increase in the number of repetitions successfully performed.

Other studies examined the impact of L-leucine on protein synthesis. Research findings published in The American Journal of Clinical Nutrition indicated that increasing the concentration of leucine in an essential amino acid supplement consumed during steady-state exercise resulted in a greater muscle protein synthesis response during recovery. And in The Journal of Nutrition, researchers determined that insulin and leucine work in synergy, allowing skeletal muscles to coordinate protein synthesis with physiological state and dietary intake.

For additional research related to L-leucine, refer to the PubMed site sponsored by the National Institutes of Health (NIH).

HGH.com Supplements With L-Leucine
Athletes, bodybuilders and fitness enthusiasts who wish to leverage the positive effects of L-leucine can find this essential amino acid in a variety of natural health and bodybuilding supplements from HGH.com:

Ana-GH – Each serving of Ana-GH contains 1.5 grams of L-leucine, which is blended with other branched-chain amino acids and active ingredients. This supplement is designed to jumpstart bulking cycles by promoting weight and mass gains while improving protein synthesis and contributing to joint and muscle repair.

Cut and Ripped Plus – Created to support cutting cycles and contest prep, Cut and Ripped Plus combines L-leucine with other active ingredients to help build muscle, increase strength and burn fat for a competition-ready physique. The capsules also help to boost energy and stamina, minimize pain, promote faster recovery and raise human growth hormone (HGH) levels.

DBol-GH – The proprietary blend of ingredients in DBol-GH includes L-leucine, which helps users to achieve lean mass and muscle growth, and also aids in muscle recovery. DBol-GH’s active ingredients are designed to stack and work together, delivering visible results and increasing HGH production.

Amino Shooter and Creatine Energy – Formulated to mix easily with cold water, Amino Shooter is used during intense workouts to protect and grow muscle. A single serving contains 3 grams of L-leucine, which supports protein synthesis and reduces muscle degradation.

Multi-Pro Chocolate Whey Protein – Each scoop of Multi-Pro Chocolate Whey provides 24 grams of protein and includes 2.16 grams of L-leucine. Fortified with vitamins and minerals, it provides a complete protein supplement for those looking to gain muscle and lose body fat.


References (Function, Sources, Benefits/Uses and Side Effects/Interactions):

Bruno, Gene. “A Primer on Branched Chain Amino Acids”; Smart Supplementation, published by Huntington College of Health Sciences; 2009. <http://www.hchs.edu/literature/BCAA.pdf>

Deuster, Patricia; Maier, Steven; et al. “Protein and Amino Acids Products – Branched Chain Amino Acids: Leucine, Isoleucine, Valine”; Dietary Supplements and Military Divers: A Synopsis for Undersea Medical Officers, published by Uniformed Services University of the Health Sciences; January 2004. <http://hprc-online.org/dietary-supplements/files/DietarySupplementUMO.pdf>

Memorial Sloan Kettering Cancer Center. “Leucine”; published under “About Herbs, Botanicals & Other Products” within Integrative Medicine area of website; last updated February 21, 2013. <http://www.mskcc.org/cancer-care/herb/leucine>

USDA Agricultural Research Service. “Leucine” search results in the National Nutrient Database for Standard Reference; accessed July 30, 2014. <http://ndb.nal.usda.gov/ndb/nutrients/index>

WebMD and Natural Medicines Comprehensive Database. “Branched Chain Amino Acids”; published under “Vitamins & Supplements”; accessed July 30, 2014. <http://www.webmd.com/vitamins-supplements/ingredientmono-1005-BRANCHED-CHAIN+AMINO+ACIDS.aspx?activeIngredientId=1005&activeIngredientName=BRANCHED-CHAIN+AMINO+ACIDS>

Research Sources:

Crowe, Melissa J.; Weatherson, Jarrad N.; and Bowden, Bruce F. “Effects of Dietary Leucine Supplementation on Exercise Performance”; European Journal of Applied Physiology; August 2006. <http://www.ncbi.nlm.nih.gov/pubmed/16265600>

Gonzalez, Adam M.; Walsh, Allyson L.; et al. “Effect of a Pre-Workout Energy Supplement on Acute Multi-Joint Resistance Exercise”; Journal of Sports Science & Medicine; June 2011. <http://www.ncbi.nlm.nih.gov/pubmed/24149870>

Norton, Layne E. and Layman, Donald K. “Branched-Chain Amino Acids in Exercise: Leucine Regulates Translation Initiation of Protein Synthesis in Skeletal Muscle after Exercise”; The Journal of Nutrition; February 2006. <http://www.ncbi.nlm.nih.gov/pubmed/16424142>

Pasiakos, Stefan M.; McClung, Holly L.; et al. “Leucine-Enriched Essential Amino Acid Supplementation During Moderate Steady State Exercise Enhances Postexercise Muscle Protein Synthesis”; The American Journal of Clinical Nutrition; September 2011. <http://www.ncbi.nlm.nih.gov/pubmed/21775557>

Thomson, Jasmine S.; Ali, Ajmol; and Rowlands, David S. “Leucine-Protein Supplemented Recovery Feeding Enhances Subsequent Cycling Performance in Well-Trained Men”; Applied Physiology, Nutrition, and Metabolism; April 2011. <http://www.ncbi.nlm.nih.gov/pubmed/21609286>




Beta-Ecdysterone Benefits, Uses, Side Effects and Functions

Function, Sources and Benefits of the Health Supplement Ingredient Beta-Ecdysterone, or 20-Hydroxyecdysone

Beta-ecdysterone – also known as 20-hydroxyecdysone, beta-ecdysone and 20-hydroxy-beta-ecdysterone – is a phytoecdysteroid, or plant-derived ecdysteroid. Ecdysterone is present within arthropods (insects and marine invertebrates) as well as various plants and fungi. The plant-based version of beta-ecdysterone is used as an ingredient in natural health and bodybuilding supplements, such as DBol-GH.

Functions of Beta-Ecdysterone

In arthropods, ecdysterone controls molting and metamorphosis. It is believed that plants produce phytoecdysteroids as a natural defense against plant-eating insects, as they can cause premature molting and other metabolic damage. Plant-derived beta-ecdysterone is structurally similar to testosterone and has been shown to affect steroid receptors in animal tests. These anabolic properties have led to its use in health and bodybuilding supplements.

Sources of Beta-Ecdysterone

While ecdysterone is naturally produced in insects, crabs and other arthropods, the type most commonly consumed by humans is extracted from plants and taken in capsule form as a natural dietary supplement. Among the many plants that contain beta-ecdysterone are Suma (Hebanthe Eriantha, also known as Brazilian Ginseng), Maral Root (Rhaponticum Carthamoides), Leuzea (Leuzea Carthamoides), Ox Knee (Achyranthes Bidentata), Giloy (Tinospora cordifolia), Serratula (Serratula Coronata) and Cyanotis Vaga.

Beta-Ecdysterone Benefits and Uses

Animal studies have shown that phytoecdysteroids play a role in protein biosynthesis; these anabolic properties suggest they may have a positive impact on human metabolism. Accordingly, beta-ecdysterone is primarily used in health and bodybuilding supplements to help increase muscle mass, enhance muscle definition, reduce body fat and improve athletic performance. Research has also indicated that beta-ecdysterone may provide other health benefits, such as protecting the cardiovascular system, suppressing degenerative diseases, improving glucose metabolism, supporting wound healing, enhancing skin condition and preventing oxidative damage to human lens epithelial cells.

Side Effects of Beta-Ecdysterone and Potential Interactions

At present, there do not appear to be any known side effects or potential interactions associated with beta-ecdysterone. However, as with any medication or health supplement, it is best to consult your physician before taking supplements containing beta-ecdysterone.

Beta-Ecdysterone Research and Studies

Numerous studies have been conducted concerning the benefits of beta-ecdysterone. Among those cited in support of its use as a bodybuilding supplement is a study by Russian researchers published in Eksperimental’naia i Klinicheskaia Farmakologiia, which found that beta-ecdysterone contributed to muscle mass increases while reducing body fat content in human subjects. Another report published by Czech scientists in Experientia indicated that beta-ecdysterone consumed by Japanese quail resulted in a 115% increase in body mass. And Diabetes, A Journal of The American Diabetes Association, reported an animal study showing that beta-ecdysterone resulted in lower body weight, improved glucose metabolism and enhanced muscle insulin signaling.

Additional benefits have emerged following international research into the use of beta-ecdysterone. Czech researchers discussed the positive biological effects of beta-ecdysterone in Natural Product Communications, theorizing that the substance has the potential to protect organisms from degenerative diseases, suppress neurodegenerative processes and protect the cardiovascular system. Menopause, The Journal of the North American Menopause Society, featured an animal study that suggested beta-ecdysterone could improve skin condition in postmenopausal women. And the International Journal of Ophthalmology published a Chinese study on senile cataracts, which found that beta-ecdysterone could inhibit oxidative damage in human lens epithelial cells

For additional research related to ecdysterone, refer to the PubMed site sponsored by the National Institutes of Health.

HGH.com Supplements With Beta-Ecdysterone

Those seeking to leverage the anabolic effects of beta-ecdysterone can find this plant-based ecdysteroid in a popular natural health and bodybuilding supplement from HGH.com:

DBol-GH – Beta-ecdysterone (20-Hydroxyecdysone) is a featured ingredient within the proprietary blend content of DBol-GH, which is formulated to increase human growth hormone (HGH) levels, build muscle and increase lean mass. The active ingredients in DBol-GH capsules are designed to stack and work together, making it a popular choice among athletes and bodybuilders seeking visible results.

References (Function, Sources, Benefits/Uses and Side Effects/Interactions):

Bruno, Gene. “20-Hydroxyecdysone: The Pro-Anabolic, Plant Steroid”; Smart Supplementation, published by Huntington College of Health Sciences; 2001. <http://www.hchs.edu/literature/20-Hyroxyecdysone.pdf>

Deuster, Patricia; Maier, Steven; et al. “Testosterone Enhancers: Ecdysterone (20-Beta-Hydroxyecdysterone)”; Dietary Supplements and Military Divers: A Synopsis for Undersea Medical Officers, published by Uniformed Services University of the Health Sciences; January 2004. <http://hprc-online.org/dietary-supplements/files/DietarySupplementUMO.pdf>

Freedman, Lisa. “Beta-Ecdysterone” in “Supplement Guide: A-Z”; Men’s Fitness website; accessed July 23, 2014. <http://www.mensfitness.com/nutrition/supplements/beta-ecdysterone>

Research Sources:

Cahlíková, Lucie; Macáková, KateĊ™ina. “Ecdysterone and its activity on some degenerative diseases”; Natural Product Communications; May 2011. <http://www.ncbi.nlm.nih.gov/pubmed/21615037>

Ehrhardt, Caroline; Wessels, Johannes T.; et al. “The Effects of 20-Hydroxyecdysone and 17β-Estradiol on the Skin of Ovariectomized Rats”; Menopause; March 2011. <http://www.ncbi.nlm.nih.gov/pubmed/21030883>




How DBOL-GH Will Help You Gain Muscle Fast | HGH's Newest Anabolic Muscle Builder

 
DBOL-GH is quickly becoming a hot item at hgh.com. One of our newest supplements to hit the market, it's another successful formula that is taking the bodybuilding world by storm.

We blogged about it here: http://blog.hgh.com/2013/09/dbol-gh-growth-hormone-supplement-now.html, DBOL is mixed with many different growth factors and ingredients that are rare to the supplement world, specifically Beta-Ecdysterone and Bovine Colostrum. 

 
Beta-Ecdysterone is a Pro-Anabolic plant steroid that is hard to find in supplements. It can be a very successful supplement when trying to build muscle that has a lot of proven science backing it up. You can read more about the science athttp://www.hgh.com/20-Hyroxyecdysone.pdf.

Bovine Colostrum  is not only formulated to give you added lean muscle mass, but also an immunity booster. Also with a lot of science behind it, Bovine Colostrum has been used by many professional bodybuilders looking to add lean mass.

With these two ingredients alone, DBOL-GH is a must add bodybuilding supplement to every serious bodybuilder or person looking to gain muscle mass. Full ingredients for DBOL-GH include:

IngredientAmount Per ServingMeasure% of DV
Proprietary Blend 2925 mg  
Proprietary Blend Content:
Beta-Ecdysterone (20-Hydroxyecdysone)
Inosine
HICA
L-Leucine
L-Isoleucine
Calcium HMB (Calcium beta-hydroxy-beta-methylbutyrate)
L-Valine
Bovine Colostrum



DBOL-GH Growth Hormone Supplement Now at HGH.com | DBOL-GH HGH.com Review

DBOL-GH is the newest Muscle Building Supplement to hit HGH.com. Mixed with different growth factors and hard to find ingredients, DBOL-GH is one of a kind and hard to find valuable supplement that should be a part of your daily intake for building muscle.

Let's review some of the ingredients in DBOL-GH and how the ingredients of DBOL-GH will help you build muscle, add mass, and act as a natural anabolic muscle supplement.

  1. Beta-Ecdysterone:  We are especially excited about this ingredient. Beta-Ecdysterone is a Pro-Anabolic plant steroid that is not commonly found in many supplements, but can be very effective in the bodybuilding supplement arena. It's, of course, a natural, safe, and legal ingredient. Beta-Ecdysterone has the science behind it that proves it will increase body mass.
    For more detailed information, you can read our press release (http://www.prweb.com/releases/2013/9/prweb11111280.htm) as well as a study here: http://www.hgh.com/20-Hyroxyecdysone.pdf
  2. Inosine: Inosine is classified as a nucleoside and is a precursor to an important energy molecule adenosine which plays many supportive roles in the body including releasing insulin and participating in oxygen metabolism and protein synthesis. Not to get too technical, Inosine has been linked to Increased energy levels, improved endurance and performance, enhanced ATP production, increased oxygen delivery, and reduced lactic acid accumulation.
  3. L-Leucine and HICA: L-Leucine is common and critical amino for muscle-building. Reviewed many times by me and included in many of our muscle builders, L-Leucine is crucial for bodybuilding because it is by far the most anabolic. Leucine is 10 times more anabolic than any other amino acid. Like other branch amino's, it is metabolized in our muscles rather than directly in the liver.  
  4. HICA is a metabolite of Leucine which aides in metabolizing and reaching the maximum potentional of the effects of Leucine, since Leucine doesn't contain HICA in itself. Since HICA can build up, it can provide a pool of leucine for post-workout recovery and cell signaling. 
  5. Calcium HMB: Calcium HMB may also have a positive affect on protein synthesis. During resistance training, calcium beta-HMB has been reported to reduce muscle catabolism, promote fat loss, increase strength and fat-free mass in athletic and nonathletic populations. 
  6. L-Valine: LV is another branched-chain amino acid found in high concentration in the muscles. It cannot be made by the body alone, and thus must be acquired through food or dietary supplements. It has a stimulating effect and is needed for muscle metabolism - Building Muscle, repairing muscle, and growth of muscle tissue, and maintaining the nitrogen balance in the body. Since it is a branched-chain amino acid, it can be used as an energy source in the muscles, and in doing so preserves the use of glucose.
  7. L-Isoleucine: L-Isoleucine will help increase endurance and help repair muscle tissue fast. During your lifting cycles, while you're tearing up your muscles, an intake of L-Isoleucine is best known for repairing and healing the muscle tissue to help it fully recover after intense exercise. It's also then literally broken down within your muscles to help increase your energy levels. You cannot eat enough foods to get enough L-Isoleucine, which is why it's best acquired thru supplements. L-Isoleucine also helps in the regulation of blood sugar.
  8. Bovine Colostrum: Increased Lean Mass and Immunity Booster. Bovine Colostrum has a lot of hype surrounding it currently. It contains a lot of growth factors. It's used in baby cows to put on nearly 100 pounds of mass; which is why it is appealing to many bodybuilders. There are many studies surrounding the benefits that Bovine Colostrum has for bodybuilders and people looking to add lean mass. In addition to its natural ability to add mass and muscle, Bovine Colostrum also helps regenerate and improve growth of aged or injured muscle, bone, cartilage, and skin collagen. This is a benefit to any adult, but especially appealing to the people over 40.






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