Discover the Function, Sources and Benefits of Somatotropin Supplements and Somatropin Injections
Somatotropin—also known as human growth hormone (HGH) or simply as growth hormone (GH)—is a polypeptide produced by somatotrope cells in the pituitary gland. It supports skeletal growth in children and adolescents, and plays a role in metabolism, body composition, muscle growth and tissue repair in adults. In addition to the somatotropin naturally produced by the body, a synthetic form of HGH called somatropin is available with a doctor’s prescription. Certain health and bodybuilding supplements may also help increase somatotropin production through natural ingredients known as HGH releasers. Many of these ingredients can be found in the proprietary-blend formulas of Somatropinne HGH, Growth Factor Plus, HGH 30,000 Nanograms, A-MAX 50, and HGF MAX, among others.
Functions of Somatotropin
Children and adolescents require somatotropin for proper growth and development; those with an HGH deficiency may require somatropin injections to achieve normal height. In adults, somatotropin helps maintain healthy tissues and organs. It can also increase bone density, muscle mass, and protein synthesis as well as decrease body fat and improve exercise capacity. Because HGH production naturally declines with age, some adults take somatotropin-boosting supplements to enhance their athletic performance and combat the physical signs of aging.
Sources of Somatotropin/Somatropin
For most individuals, the primary source of somatotropin is the body’s endogenous production by the somatotropic cells of the pituitary gland. The body produces its highest levels of somatotropin during childhood and adolescence; these levels significantly decline when the individual reaches full adult height. Scientists have also developed a synthetic form of somatotropin known as somatropin or somatrem, using E. coli or mammalian cells to create therapeutic proteins in a laboratory setting. Somatropin is chemically identical to the somatotropin that is produced by the pituitary gland and administered by subcutaneous injection. It is a regulated substance, which means it can only be legally prescribed for FDA-approved uses.
Since somatropin injections are not legally available to healthy adults, those seeking the benefits of somatotropin may opt to take natural supplements that are designed to boost the body’s own HGH production. Certain amino acids are recognized as natural HGH releasers—including GABA, arginine, ornithine, glutamine, lysine, tyrosine and glycine—so dietary supplements containing these ingredients may help increase somatotropin levels.
Somatropin Benefits and Uses
The pituitary gland’s secretion of somatotropin supports bodily growth and development throughout childhood and adolescence, so the most common reason for prescribing somatropin is to treat children and teens with HGH deficiency or specific medical conditions. FDA-approved pediatric uses of somatropin include idiopathic growth hormone deficiency, Noonan syndrome, Turner syndrome, Prader-Willi syndrome, chronic renal insufficiency, short stature homeobox-containing gene (SHOX) deficiency, and idiopathic short stature.
Although HGH levels naturally decline with age, somatotropin continues to play a role throughout adulthood—helping to regulate metabolism and protein synthesis and promoting organ, tissue and bone health. Somatropin may be legally prescribed to adults who have severe HGH deficiency, which normally occurs due to a pituitary adenoma (tumor) or adenoma-related surgery or radiation treatments. It is also sometimes prescribed to prevent or minimize wasting in AIDS patients.
Somatropin injections can improve bone density, muscle mass and exercise capacity in adults with HGH deficiency, and they can produce similar outcomes in healthy adults. As a result, some bodybuilders and athletes take somatropin to enhance their athletic performance and physique. However, it should be noted that somatropin cannot legally be prescribed for such purposes. Furthermore, the World Anti-Doping Agency (WADA), International Olympic Committee and numerous sports organizations have banned the use of HGH injections among athletes.
Given the potential repercussions associated with illegal somatropin injections, many bodybuilders, athletes and aging adults have starting taking natural HGH supplements to help the body increase its own somatotropin production. Proponents of somatotropin-boosting supplements report that these natural HGH releasers have helped them develop lean muscle, improve their strength and endurance, and recover from intense workouts and injuries more quickly. They also credit HGH supplements with enhancing their body composition and slowing the visible signs of aging.
Somatropin Side Effects
Individuals considering HGH injections should be aware of somatropin side effects and interactions. Some users have experienced an allergic reaction, with symptoms such as itching or rashes, chest pain, difficulty breathing, or swelling of the face, tongue, or throat. Other possible side effects include headaches, nausea, vomiting, blurred vision, fluid retention, swelling of the hands or feet, muscle stiffness or pain, and burning, tingling or numbness in the skin. Somatropin may increase the risk of developing diabetes, cancer or pancreatitis, and it can cause dislocation of the hipbone that results in limping or knee/hip pain. Interactions have been recorded when somatropin is used with estrogen hormone replacement or glucocorticoids (such as prednisone or hydrocortisone), and somatropin can cause adverse effects in patients with diabetes, scoliosis, kidney disease and certain other medical conditions.
Somatotropin-boosting HGH supplements tend to have fewer and less severe side effects than somatropin injections; however, the side effects and interactions will vary depending on the supplement’s ingredients.
More detailed safety information on somatropin side effects, interactions and precautions can be found on the Mayo Clinic website. For natural somatotropin-boosting supplements, refer to the relevant ingredient articles on HGH.com to learn about potential side effects and interactions. As with any medication or health supplement, it is best to consult your physician before using somatropin injections or natural HGH supplements.
Somatotropin/Somatropin Research and Studies
Researchers have conducted numerous studies on both the natural and synthetic forms of somatotropin. Visit the PubMed site sponsored by the National Institutes of Health (NIH) to explore the latest somatotropin research and somatropin studies. For research on specific ingredients that have been shown to boost somatotropin levels, refer to the corresponding ingredient articles on the HGH.com blog.
You will discover there is a wealth of information on at HGH.com. We recently posted this related blog post on HGH/somatotropin: Human Growth Hormone (HGH) Benefits, Uses, Side Effects and Functions.
HGH.com Supplements With Natural Somatotropin/HGH Releasers
Many of the health and bodybuilding supplements available from HGH.com are formulated to naturally increase somatotropin/HGH levels. These products include:
Somatropinne HGH – Purity Select’s natural Somatropinne HGH capsules contain a proprietary blend of L-arginine, cowhage, maca and horny goat weed. As an over-the-counter somatotropin releaser, this supplement is formulated to help athletes gain lean muscle and increased energy while also providing weight-loss and anti-aging benefits.
HGH 30,000 Nanograms Pills and HGH 30,000 Nanograms Spray –Purity Select’s 30,000 Nanogram HGH pills and spray are designed to promote somatotropin production, muscle growth, increased energy and other health benefits. They contain a powerful combination of amino acids—including L-glutamine, L-arginine, L-ornithine, L-lysine, L-glycine, L-valine and L-tyrosine —as well as other natural ingredients such as colostrum, GABA, cowhage (mucuna pruriens), long jack and deer antler velvet.
Growth Factor Plus – As its name suggests, Growth Factor Plus is intended to support height growth as well as bone and joint health. Its proprietary blend of ingredients features amino acids such as L-arginine, L-ornithine, L-lysine, L-glycine, L-glutamine, and L-tyrosine.
HGF MAX – Purity Select HGF MAX is intended to boost somatotropin production, improve muscle tone, build muscle, promote fat loss, boost energy and increase metabolism. Its proprietary blend of ingredients includes arginine, GABA, glutamine, lysine, glycine, tyrosine, ornithine and deer antler velvet.
Ana-GH – These capsules contain a blend of L-group amino acids such as L-leucine and L-valine as well as plant-based ingredients such as horny goat weed and maca. Ana-GH is intended to jumpstart bulking cycles by promoting muscle mass and weight gains, improving protein synthesis, and contributing to joint and muscle repair.
Anapolan-MAX 50 (A-MAX 50) – Anapolan-MAX is formulated to support lean muscle gain while boosting somatotropin production and testosterone levels. Its proprietary blend of ingredients includes L-tyrosine, Tribulus terrestris, cowhage (mucuna pruriens), shilajit and dehydroepiandrosterone.
ClenXDV – Featuring a proprietary blend of DHEA, deer antler velvet, wild yam, Tribulus terrestris and other natural ingredients, ClenXDV is intended to help athletes and bodybuilders build muscle, lose weight and burn fat.
DBol-GH – This anabolic lean muscle gainer is designed to promote lean mass and muscle growth, support muscle recovery and naturally boost HGH levels with a proprietary blend of ingredients that include bovine colostrum, beta-ecdysterone, L-valine and L-leucine.
Dekka – With a blend of Korean ginseng root, yucca bark, wild yam root, and dehydroepiandrosterone, Dekka capsules are formulated to help bodybuilders achieve lean mass, weight gain, muscle building and bulking.
Testosterone Plus – HGH Testosterone Plus features a proprietary blend of long jack, maca, Tribulus terrestris, ginkgo biloba and other natural ingredients that are intended to help build muscle, aid in muscle recovery and boost energy while offering sexual health benefits such as improved libido and stamina.
RoidX Juice – The ingredients in RoidX Juice are designed to help bodybuilders quickly develop muscle and gain weight in addition to supporting muscle recovery. RoidX Juice capsules contain a proprietary blend of Vitamin E, Tribulus terrestris, shilajit and dehydroepiandrosterone.
Winstrol Max – Optimized for cutting cycles, Winstrol Max is formulated to promote lean mass gain and help athletes achieve ripped abs. Its powerful blend of ingredients includes L-group amino acids such as leucine, arginine and valine as well as oat straw (Avena sativa) extract and saw palmetto.
Drug Enforcement Administration. “Human Growth Hormone”; DEA fact sheet; August 2013. <http://www.deadiversion.usdoj.gov/drug_chem_info/hgh.pdf>
U.S. Food and Drug Administration (FDA). “Somatropin Information”; published under “Drug Safety and Availability”; August 4, 2011. <http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm237839.htm>
Kamionka, Mariusz. “Engineering of Therapeutic Proteins Production in Escherichia Coli”; Current Pharmaceutical Biotechnology; February 2011. <http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179032>
Mayo Clinic. “Somatropin, E-Coli Derived (Subcutaneous Route, Injection Route)”; Mayo Clinic website; last updated April 1, 2015. <http://www.mayoclinic.org/drugs-supplements/somatropin-e-coli-derived-subcutaneous-route-injection-route/description/drg-20071575>
Mayo Clinic. “Somatropin, Mammalian Derived (Injection Route, Subcutaneous Route)”; Mayo Clinic website; last updated April 1, 2015. <http://www.mayoclinic.org/drugs-supplements/somatropin-mammalian-derived-injection-route-subcutaneous-route/description/drg-20071668>
WebMD. “Somatropin Injection”; accessed June 9, 2015. <http://www.webmd.com/drugs/2/drug-6259/somatropin-injection/details>